子宫苗勒管异常患者剖宫产术后试产及阴道分娩的研究:一项基于人群的研究。
Trial of labor and vaginal birth after cesarean section in patients with uterine Müllerian anomalies: a population-based study.
作者信息
Erez Offer, Dukler Doron, Novack Lena, Rozen Amit, Zolotnik Leonid, Bashiri Asher, Koifman Arie, Mazor Moshe
机构信息
Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
出版信息
Am J Obstet Gynecol. 2007 Jun;196(6):537.e1-11. doi: 10.1016/j.ajog.2007.01.012.
OBJECTIVE
The aim of our study was to determine the success rate of vaginal birth after cesarean section among patients with Müllerian anomalies in comparison to the success rate of vaginal birth after cesarean section in patients with normal uterus with emphasis on the rate of uterine rupture.
STUDY DESIGN
A retrospective population-based study was designed, including all patients with a previous cesarean section that attempted vaginal birth after cesarean section during the study period. Women with known Müllerian anomalies were included in the study group. The control group consisted of women with normal uterus. The rates of vaginal birth after cesarean section, uterine rupture, maternal morbidity, and perinatal outcome were compared between the groups.
RESULTS
Of 5571 eligible patients, 165 (2.96%) had Müllerian anomalies. The rate of vaginal birth after cesarean section was significantly lower among patients with Müllerian anomalies than in patients with normal uterus, 37.6% (62/165) vs 50.7% (2740/5406), respectively (P = .0009). During the study period, there were 10 cases of uterine rupture, all in patients with normal uterus. The major indication for repeated cesarean delivery among Müllerian anomalies patients was malpresentation, 58.3% (60/103) vs 14.4% (385/2666) in patients with normal uterus (P < .001).
CONCLUSION
A trial of vaginal birth after cesarean section in patients with uterine Müllerian malformations and cephalic presentation is not associated with a higher rate of maternal morbidity and uterine rupture.
目的
我们研究的目的是确定患有苗勒管异常的患者剖宫产术后经阴道分娩的成功率,并与子宫正常患者剖宫产术后经阴道分娩的成功率进行比较,重点关注子宫破裂率。
研究设计
设计了一项基于人群的回顾性研究,纳入研究期间所有既往有剖宫产史且尝试剖宫产术后经阴道分娩的患者。已知患有苗勒管异常的女性被纳入研究组。对照组由子宫正常的女性组成。比较两组之间剖宫产术后经阴道分娩率、子宫破裂率、孕产妇发病率和围产期结局。
结果
在5571例符合条件的患者中,165例(2.96%)患有苗勒管异常。患有苗勒管异常的患者剖宫产术后经阴道分娩率显著低于子宫正常的患者,分别为37.6%(62/165)和50.7%(2740/5406)(P = 0.0009)。在研究期间,有10例子宫破裂病例,均发生在子宫正常的患者中。苗勒管异常患者再次剖宫产的主要指征是胎位异常,为58.3%(60/103),而子宫正常患者为14.4%(385/2666)(P < 0.001)。
结论
子宫苗勒管畸形且为头先露的患者进行剖宫产术后经阴道分娩试验,与较高的孕产妇发病率和子宫破裂率无关。