Bürgi U
Abteilung für Endokrinologie und Diabetologie, Inselspital, Bern.
Ther Umsch. 1991 Nov;48(11):741-5.
Many endocrine diseases can cause fatigue. Tiredness is a frequent symptom of primary and secondary hypothyroidism, hyperthyroidism, excessive glucocorticoid or mineralocorticoid production, primary and secondary adrenal insufficiency, primary and secondary hypogonadism and hyperprolactinemia in the male, acromegaly, diabetes mellitus and diabetes insipidus. A great number of medical diseases other than those mentioned in the articles on cardiological and pneumological fatigue can also cause abnormal tiredness (infectious diseases, hematological, renal, hepatic, gastrointestinal and rheumatological disturbances, vasculitis and malignant tumors). The pathogenesis of tiredness caused by endocrine or medical illnesses, i.e. how the sensation of fatigue is produced, is not clear. The fatigue of the various endocrine or other medical diseases is not disease-specific, i.e. its characteristics do not differentiate it from the fatigue of other illnesses.
许多内分泌疾病都会导致疲劳。疲倦是原发性和继发性甲状腺功能减退、甲状腺功能亢进、糖皮质激素或盐皮质激素分泌过多、原发性和继发性肾上腺功能不全、原发性和继发性性腺功能减退以及男性高催乳素血症、肢端肥大症、糖尿病和尿崩症的常见症状。除了关于心脏和肺部疲劳的文章中提到的疾病外，大量其他医学疾病也会导致异常疲倦（传染病、血液学、肾脏、肝脏、胃肠道和风湿病紊乱、血管炎和恶性肿瘤）。内分泌或内科疾病引起疲劳的发病机制，即疲劳感是如何产生的，尚不清楚。各种内分泌或其他内科疾病引起的疲劳并非疾病特异性的，也就是说，其特征并不能将其与其他疾病引起的疲劳区分开来。
