Drabe Natalie, Zwahlen Diana, Büchi Stefan, Moergeli Hanspeter, Zwahlen Roger A, Jenewein Josef
Department of Psychiatry, University Hospital, Zurich, Switzerland.
Psychooncology. 2008 Feb;17(2):199-204. doi: 10.1002/pon.1199.
The diagnosis of cancer not only affects the lives of patients but also the lives of their relatives. The aim of this study was to investigate the prevalence of psychiatric disorders and quality of life (QoL) among wives of patients treated for head and neck cancer (HNC). We examined 31 wives of patients treated for HNC from January 1998 to December 2004 (meantime since diagnosis 3.7 years) by questionnaires with regard to quality of life (WHOQOL-BREF), quality of the relationship (Dyadic Adjustment Scale), and affective symptoms (Hospital Anxiety and Depression Scale, HADS). Prevalence of psychiatric morbidity was measured by the Mini International Neuropsychiatric Interview (MINI). Results indicated that QoL and satisfaction with the relationship were comparable to the normal population. HADS mean scores showed no clinically relevant levels of depression and anxiety. A high prevalence of psychiatric disorders (38.7%, particularly agoraphobia) was found in the MINI. Wives diagnosed with an anxiety disorder reported significantly lower QoL compared to those without. The results of this study suggest that agoraphobia is a frequent psychiatric disorder seen in wives of HNC patients. Diagnosis of HNC can have a strong impact on the mental health of the spouse and should be taken in account in counselling of HNC patients.
癌症的诊断不仅会影响患者的生活，还会影响其亲属的生活。本研究的目的是调查接受头颈部癌（HNC）治疗的患者的妻子中精神障碍的患病率和生活质量（QoL）。我们通过问卷调查，对1998年1月至2004年12月期间接受HNC治疗的患者的31名妻子（诊断后平均时间为3.7年）进行了生活质量（世界卫生组织生活质量简表，WHOQOL - BREF）、关系质量（二元调适量表）和情感症状（医院焦虑抑郁量表，HADS）方面的调查。通过迷你国际神经精神访谈（MINI）测量精神疾病的患病率。结果表明，生活质量和对关系的满意度与正常人群相当。HADS平均得分显示没有临床相关水平的抑郁和焦虑。在MINI中发现精神障碍的患病率很高（38.7%，尤其是广场恐惧症）。与未被诊断出焦虑症的妻子相比，被诊断出焦虑症的妻子报告的生活质量显著更低。本研究结果表明，广场恐惧症是HNC患者妻子中常见的精神障碍。HNC的诊断可能会对配偶的心理健康产生强烈影响，在对HNC患者进行咨询时应予以考虑。
