Berend Keith R, Lombardi Adolph V, Adams Joanne B
Joint Implant Surgeons, Inc, New Albany, Ohio, USA.
Orthopedics. 2007 May;30(5 Suppl):19-23.
Standard surgical criteria for unicondylar knee arthroplasty exclude patients who weigh >82 kg (187 lbs), patients aged <60 years, and patients with more than minimal erosive changes in the patellofemoral articulation, indicated clinically by anterior knee pain. In April 2004, the US Food and Drug Administration approved the Oxford phase 3 unicondylar prosthesis for implantation during unicompartmental knee arthroplasty. Since this broader indication was adopted, the implant has proven to be a bone- and ligament- conservative yet long-lasting intervention for anteromedial arthritis of the knee. The purpose of this study is to investigate the early outcomes of unicompartmental medial knee arthroplasty using the Oxford prosthesis in US patients who do not meet the standard inclusion criteria. Specifically, the current study investigates the impact of obesity, young age, patellofemoral arthritis, and isolated medial knee pain on the early outcomes of this device. In this large series of 318 unicompartmental knee arthroplasties performed in 270 patients, these standard preoperative contraindications had no influence on the successful outcome of the procedure using the Oxford phase 3 device.
单髁膝关节置换术的标准手术标准排除了体重>82公斤（187磅）的患者、年龄<60岁的患者以及髌股关节有明显侵蚀性改变（临床症状为膝前疼痛）的患者。2004年4月，美国食品药品监督管理局批准了牛津3期单髁假体用于单间室膝关节置换术中植入。自从采用了这一更宽泛的适应证以来，该植入物已被证明是一种对膝关节前内侧关节炎而言既保留骨骼和韧带又持久耐用的干预措施。本研究的目的是调查在美国不符合标准纳入标准的患者中使用牛津假体进行单间室内侧膝关节置换术的早期结果。具体而言，本研究调查肥胖、年轻、髌股关节炎和单纯内侧膝关节疼痛对该装置早期结果的影响。在对270例患者进行的这一大系列318例单间室膝关节置换术中，这些标准术前禁忌证对使用牛津3期装置的手术成功结果没有影响。
