de Vries Jutte J C, van Assen Sander, Mulder André B, Kampinga Greetje A
Department of Medical Microbiology, University Medical Center Groningen, The Netherlands.
Am J Trop Med Hyg. 2007 Jun;76(6):1098-9.
An adult traveler presented with fever and malaise after returning from Sierra Leone. Young trophozoites of Plasmodium falciparum were seen in a blood smear, with parasitemia being 10%. Moreover, blood cultures drawn on admission signaled as "positive" after 1 day of incubation, but no bacteria were seen in the Gram stain or were subcultured. A Giemsa-stained smear from the positive bottle contents yielded numerous pigmented, mature trophozoites of P. falciparum. This case indicates that, in patients with malaria, the growth of P. falciparum in blood cultures can result in "false"-positive blood cultures.
一名成年旅行者从塞拉利昂返回后出现发热和不适。在血涂片上可见恶性疟原虫的年轻滋养体,疟原虫血症为10%。此外,入院时采集的血培养物在培养1天后显示“阳性”,但革兰氏染色未发现细菌,也未进行亚培养。对阳性瓶内容物进行吉姆萨染色涂片,发现大量有色素的成熟恶性疟原虫滋养体。该病例表明,在疟疾患者中,恶性疟原虫在血培养中的生长可导致血培养“假”阳性。