Dinnerstein Eric, Collins Deborah, Berman Stephen A
Section of Neurology, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA.
Cogn Behav Neurol. 2007 Jun;20(2):136-7. doi: 10.1097/WNN.0b013e31804c701e.
Stiff person syndrome (SPS) is an uncommon disorder characterized by progressive muscle stiffness, rigidity, and axial muscle spasms. It is presumed to be an autoimmune process, with glutamic acid decarboxylase antibodies present in most cases. Here, we present a case report of a patient diagnosed with post-traumatic stress disorder (PTSD) acquired by sexual trauma and by exposure to the severely wounded soldiers she attended as a nurse. Subsequently, she developed SPS confirmed by serology. The possibility of an association between PTSD and SPS is theorized, given their relationship to the GABAergic system. Further studies examining the relation between PTSD and SPS should be initiated.
僵人综合征（SPS）是一种罕见的疾病，其特征为进行性肌肉僵硬、强直和轴性肌肉痉挛。推测它是一种自身免疫性疾病，大多数病例中存在谷氨酸脱羧酶抗体。在此，我们报告一例患者，该患者因性创伤以及作为护士照料重伤士兵而患上创伤后应激障碍（PTSD）。随后，她经血清学确诊患上僵人综合征。鉴于创伤后应激障碍和僵人综合征与γ-氨基丁酸能系统的关系，理论上推测二者之间可能存在关联。应启动进一步研究以探讨创伤后应激障碍与僵人综合征之间的关系。
