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体外膜肺氧合支持下的劈开腹壁肌瓣修补术治疗大型先天性膈疝

The split abdominal wall muscle flap repair for large congenital diaphragmatic hernias on extracorporeal membrane oxygenation.

作者信息

Brant-Zawadzki Peter B, Fenton Stephen J, Nichol Peter F, Matlak Michael E, Scaife Eric R

机构信息

Department of Surgery, University of Utah, Salt Lake City, UT 84132, USA.

出版信息

J Pediatr Surg. 2007 Jun;42(6):1047-50; discussion 1051. doi: 10.1016/j.jpedsurg.2007.01.041.

Abstract

BACKGROUND

Numerous techniques exist for repairing large congenital diaphragmatic hernias (CDHs) including prosthetic patches, tissue-engineered grafts, and various muscle flaps. A split abdominal wall muscle flap is a simple, durable way to repair a large diaphragmatic hernia. This technique has not gained widespread use, and some have suggested that it would be inappropriate in the setting of extracorporeal membrane oxygenation (ECMO) because of bleeding risk. We present our series of diaphragmatic hernias with a focus on those repaired with the split abdominal wall technique while on ECMO.

METHODS

A retrospective, single-institution chart review was performed on all patients who underwent surgical repair for CDH over 6 years beginning in August 2000.

RESULTS

Seventy-five patients underwent repair. Sixteen were performed with patients on ECMO. Of these, 4 were closed primarily, 7 used a prosthetic patch, and 5 used a split abdominal wall muscle flap. Two patients in the prosthetic group developed a recurrent hernia, and 2 required reoperation for bleeding while on ECMO. No reoperations for bleeding were required in the abdominal muscle flap group.

CONCLUSIONS

The split abdominal wall muscle flap can be safely performed on anticoagulated patients. We believe it is a practical option for repairing large CDHs.

摘要

背景

存在多种修复大型先天性膈疝(CDH)的技术,包括人工补片、组织工程移植物和各种肌瓣。腹壁劈开肌瓣是修复大型膈疝的一种简单、持久的方法。该技术尚未得到广泛应用,一些人认为在体外膜肺氧合(ECMO)情况下使用该技术不合适,因为存在出血风险。我们展示我们的一系列膈疝病例,重点关注在ECMO支持下采用腹壁劈开技术修复的病例。

方法

对2000年8月开始的6年期间所有接受CDH手术修复的患者进行了一项回顾性、单机构病历审查。

结果

75例患者接受了修复手术。16例是在患者接受ECMO支持时进行的。其中,4例进行了一期缝合,7例使用了人工补片,5例使用了腹壁劈开肌瓣。人工补片组有2例出现复发性疝,2例在ECMO支持期间因出血需要再次手术。腹壁肌瓣组无需因出血进行再次手术。

结论

腹壁劈开肌瓣可在抗凝患者中安全实施。我们认为它是修复大型CDH的一种实用选择。

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