Zhang Wei-Dong, Xie Chuan-Miao, Mo Yun-Xian, Li Jia-Yao
State Key Laboratory of Oncology in South China, Guangzhou, Guangdong 510060, P. R. China.
Ai Zheng. 2007 Jun;26(6):643-6.
BACKGROUND & OBJECTIVE: It's difficult to distinguish peripheral primitive neuroectodermal tumor (PNET) from other small round cell tumors such as Ewing's sarcoma by histological examination. This study was to analyze the CT and MRI features of peripheral PNET.
The CT and MRI records of 7 patients with pathologically proved peripheral PNET were reviewed.
The tumors were located in the left ala nasi, right lower jaw bone, left chest wall, right chest wall, left spermatic cord, paraspinal, and lumbar vertebral canal. The tumors in soft tissue showed resembled non-calcified, ill-defined soft tissue masses with cystic or necrotic areas on CT images, with heterogeneous enhancement on contrast images. The tumors in the bone showed lytic lesions with large soft tissue masses on CT images. The tumors in the paraspinal and vertebral canal showed well-defined soft tissue masses without involving cord and cauda equine on MRI, and showed isointensity or hypointensity on T1WI and isointensity or hyperintensity on T2WI.
The imaging features of peripheral PNET are non-specific. CT and MRI are useful in delineating the extent, finding distant metastasis, predicting respectability and monitoring treatment of peripheral PNET.
通过组织学检查很难将外周原始神经外胚层肿瘤(PNET)与其他小圆细胞肿瘤如尤因肉瘤区分开来。本研究旨在分析外周PNET的CT和MRI特征。
回顾7例经病理证实的外周PNET患者的CT和MRI记录。
肿瘤位于左鼻翼、右下颌骨、左胸壁、右胸壁、左精索、脊柱旁和腰椎管。软组织中的肿瘤在CT图像上表现为类似非钙化、边界不清的软组织肿块,伴有囊性或坏死区域,增强图像上呈不均匀强化。骨内肿瘤在CT图像上表现为溶骨性病变伴大的软组织肿块。脊柱旁和椎管内肿瘤在MRI上表现为边界清晰的软组织肿块,不累及脊髓和马尾,T1WI呈等信号或低信号,T2WI呈等信号或高信号。
外周PNET的影像学特征不具有特异性。CT和MRI有助于明确外周PNET的范围、发现远处转移、预测可切除性及监测治疗情况。