D'Ippolito R, Foresi A, Castagnetti C, Gesualdi S, Castagnaro A, Marangio E, Olivieri D
Department of Clinical Sciences, Section of Respiratory Diseases, University of Parma, Parma, Italy.
Monaldi Arch Chest Dis. 2007 Mar;67(1):23-9. doi: 10.4081/monaldi.2007.506.
To evaluate the indications and the safety of fiberoptic bronchoscopy (FOB) with bronchoalveolar lavage (BAL), protected specimen brushing (PSB), endobronchial biopsy (EBB), and transbronchial biopsy (TBB) in a population of very elderly patients.
We performed a retrospective study of all adult patients, aged 50 years or older, who underwent FOB in the Bronchology Unit of the University of Parma Hospital between 1 January, 2003 and 31 April, 2005. Bronchoscopy records of 436 consecutive patients, including 191 patients, 75 yrs of age and older ("very elderly"; = > 75 yrs), were reviewed.
Patients aged < 75 years and aged =/> 75 years were no different with regard to gender, BMI, baseline FEV1/FVC ratio, baseline SaO2, and blood pressure. The primary indication in patients aged < 75 years, was to assist in the diagnosis of a pulmonary mass of unknown aetiology (33%) and to remove secretions in the very elderly patients (31%). Indications for FOB and sampling procedures in the two groups were similar. Approximately 30% of patients in each group required supplemental oxygen during the procedure and fever occurred in 9.2% and 10.3% of patients, respectively. Hypertension and bleeding were relatively rare and did not occur more often in the very elderly.
Indication for FOB did not vary with age and adverse events in both groups were uncommon and generally not severe.
评估在高龄患者群体中,纤维支气管镜检查(FOB)联合支气管肺泡灌洗(BAL)、防污染样本毛刷采样(PSB)、支气管活检(EBB)及经支气管活检(TBB)的适应证及安全性。
我们对2003年1月1日至2005年4月31日期间在帕尔马大学医院支气管病科接受FOB检查的所有50岁及以上成年患者进行了一项回顾性研究。回顾了436例连续患者的支气管镜检查记录,其中包括191例年龄在75岁及以上(“高龄”;≥75岁)的患者。
年龄<75岁和≥75岁的患者在性别、体重指数、基线FEV1/FVC比值、基线SaO2及血压方面无差异。年龄<75岁患者的主要适应证是协助诊断病因不明的肺部肿块(33%),而在高龄患者中主要是清除分泌物(31%)。两组FOB及采样程序的适应证相似。每组约30%的患者在检查过程中需要补充氧气,发热分别发生在9.2%和10.3%的患者中。高血压和出血相对少见,在高龄患者中发生频率并未更高。
FOB的适应证不随年龄变化,两组的不良事件均不常见且一般不严重。