Papinniemi Marjo, Keski-Nisula Leea, Heinonen Seppo
Department of Obstetrics and Gynecology, Kuopio University and University Hospital, Kuopio, Finland.
Am J Perinatol. 2007 Jun;24(6):353-7. doi: 10.1055/s-2007-984403. Epub 2007 Jun 12.
The purpose of this study was to explore the maternal risk profile and obstetric outcome in pregnancies affected by placenta previa. Retrospective case-control study involved all women (93 [0.37%] women with diagnosed placenta previa and 24,857 unaffected controls) who gave birth to singleton infants at Kuopio University Hospital between the years 1989 and 2000. Grand multiparity, infertility problems, and advanced maternal age were independent risk factors of placenta previa, with adjusted relative risks of 5.8, 3.7, and 2.4, respectively. Most women with placenta previa (88.2%) underwent cesarean delivery before term. They also more often had velamentous umbilical cord insertion (7.5%) and higher placental-to-birthweight ratios than the controls. Placenta previa was associated with risks of preterm delivery, low birthweight infants, and need for neonatal intensive care, at odds ratios of 27.7, 7.4, and 3.4, respectively. In conclusion, placenta previa is an infrequent pregnancy complication associated with multiparity, advanced maternal age, infertility problems, elevated placental ratio, and velamentous umbilical cord insertion.
本研究的目的是探讨前置胎盘妊娠的孕产妇风险概况及产科结局。回顾性病例对照研究纳入了1989年至2000年间在库奥皮奥大学医院分娩单胎婴儿的所有女性（93例[0.37%]诊断为前置胎盘的女性和24,857例未受影响的对照者）。多产、不孕问题和高龄产妇是前置胎盘的独立危险因素，调整后的相对风险分别为5.8、3.7和2.4。大多数前置胎盘女性（88.2%）在足月前接受了剖宫产。她们也更常出现帆状脐带附着（7.5%），且胎盘与出生体重之比高于对照组。前置胎盘与早产、低体重儿及新生儿重症监护需求风险相关，比值比分别为27.7、7.4和3.4。总之，前置胎盘是一种罕见的妊娠并发症，与多产、高龄产妇、不孕问题、胎盘比值升高及帆状脐带附着有关。
