Weizsaecker K, Deaver J E, Cohen W R
Department of Obstetrics and Gynecology, Jamaica Hospital Medical Center, New York, NY 11418, USA.
BJOG. 2007 Aug;114(8):1003-9. doi: 10.1111/j.1471-0528.2007.01392.x. Epub 2007 Jun 12.
To determine risk factors for Erb's palsy, with a focus on graphic labour patterns.
A case-control study.
New York City.
A total of 45 consecutive cases of Erb's palsy and 90 controls.
Pregnancies and labours of neonatal Erb's palsy cases were compared with 90 controls using univariate and multiple logistic regression analysis.
Erb's palsy and shoulder dystocia.
Mothers of children with Erb's palsy had a higher term body mass index and more gestational diabetes than those of controls. Even cases without diabetes had higher blood glucose values after a 50-g glucose challenge than did controls. Cases had a higher birthweight and a lower ratio of head-to-thoracic circumference than controls. Shoulder dystocia occurred in 67% of cases and in 2% of controls (P = 0.001). Only 46% of labours had a completely normal dilatation pattern. In a multiple logistic regression model, variables independently associated with brachial plexus injury were long deceleration phase of labour, long second stage, high birthweight, black race, and high neonatal or maternal body mass.
Erb's palsy was frequently preceded by abnormal labour and shoulder dystocia; however, a substantial proportion of cases occurred after normal labour and delivery. Predictive models will be necessary to determine to what extent careful monitoring of the terminal portion of dilatation and of fetal descent and incorporation of maternal body mass and race (all independent risk factors in this study) will help identify fetuses at risk for brachial plexus palsy.
确定臂丛神经麻痹的危险因素,重点关注产程图模式。
病例对照研究。
纽约市。
共45例连续的臂丛神经麻痹病例和90例对照。
采用单因素和多因素逻辑回归分析,将新生儿臂丛神经麻痹病例的妊娠和分娩情况与90例对照进行比较。
臂丛神经麻痹和肩难产。
与对照组相比,臂丛神经麻痹患儿的母亲足月时体重指数更高,妊娠期糖尿病更多。即使是无糖尿病的病例,在进行50克葡萄糖耐量试验后血糖值也高于对照组。病例组出生体重更高,头胸周长比低于对照组。67%的病例发生肩难产,对照组为2%(P = 0.001)。只有46%的产程有完全正常的扩张模式。在多因素逻辑回归模型中,与臂丛神经损伤独立相关的变量有产程减速期延长、第二产程延长、出生体重高、黑人种族以及新生儿或母亲体重高。
臂丛神经麻痹常先于异常产程和肩难产出现;然而,相当一部分病例发生在正常分娩之后。需要建立预测模型,以确定对扩张末期、胎儿下降情况进行仔细监测以及纳入母亲体重和种族(本研究中的所有独立危险因素)在多大程度上有助于识别有臂丛神经麻痹风险的胎儿。