Suppr超能文献

“按时服药”:溃疡性结肠炎患者的不依从问题

"Take your medicine": nonadherence issues in patients with ulcerative colitis.

作者信息

Turnbough Lisa, Wilson Lindsay

机构信息

GI Division, Johns Hopkins University, Baltimore, Maryland, USA.

出版信息

Gastroenterol Nurs. 2007 May-Jun;30(3):212-7; quiz 218-9. doi: 10.1097/01.SGA.0000278170.13059.e9.

Abstract

Ulcerative colitis is a lifelong disease causing inflammation and ulceration of the colon. Symptoms of ulcerative colitis include abdominal pain, bloody diarrhea, bloating, and fecal urgency. The current standard therapy for mild to moderate ulcerative colitis is the use of 5-aminosalicylates, with patients requiring continuous treatment to maintain remission. A substantial proportion of patients, however, are nonadherent to prescribed 5-aminosalicylate treatment regimens, resulting in a greater chance of disease relapse with severe associated symptoms. There are many reasons why a patient with ulcerative colitis may be nonadherent including the patient's perception of the condition or a lack of understanding about the disease or treatment. Multiple daily dosing or rectal administration of 5-aminosalicylate medications also can adversely affect adherence rates. Because gastrointestinal nurses often are the primary points of contact for patients with ulcerative colitis, they are in a unique position to take simple steps that will improve adherence rates and thus increase the efficacy of prescribed therapy. This article highlights important aspects of education and patient care for patients with ulcerative colitis.

摘要

溃疡性结肠炎是一种导致结肠炎症和溃疡的终身性疾病。溃疡性结肠炎的症状包括腹痛、血性腹泻、腹胀和排便急迫感。轻度至中度溃疡性结肠炎的当前标准疗法是使用5-氨基水杨酸酯,患者需要持续治疗以维持缓解。然而,相当一部分患者不遵守规定的5-氨基水杨酸酯治疗方案,导致疾病复发的可能性更大,并伴有严重的相关症状。溃疡性结肠炎患者不遵守治疗方案有许多原因,包括患者对病情的认知或对疾病或治疗缺乏了解。5-氨基水杨酸酯药物的每日多次给药或直肠给药也会对依从率产生不利影响。由于胃肠科护士通常是溃疡性结肠炎患者的主要接触点,他们处于独特的位置,可以采取简单的措施来提高依从率,从而提高规定治疗的疗效。本文重点介绍了溃疡性结肠炎患者教育和患者护理的重要方面。

相似文献

1
"Take your medicine": nonadherence issues in patients with ulcerative colitis.
Gastroenterol Nurs. 2007 May-Jun;30(3):212-7; quiz 218-9. doi: 10.1097/01.SGA.0000278170.13059.e9.
2
Oral 5-aminosalicylic acid therapy for mild-to-moderate ulcerative colitis.
J Am Acad Nurse Pract. 2010 Nov;22(11):586-92. doi: 10.1111/j.1745-7599.2010.00558.x. Epub 2010 Oct 19.
3
Mesalamine once daily is more effective than twice daily in patients with quiescent ulcerative colitis.
Clin Gastroenterol Hepatol. 2009 Jul;7(7):762-9. doi: 10.1016/j.cgh.2009.04.004. Epub 2009 Apr 16.
4
Novel 5-aminosalicylic acid formulations in ulcerative colitis: old dog, new tricks.
Gastroenterol Nurs. 2008 Jul-Aug;31(4):286-92. doi: 10.1097/01.SGA.0000334035.94370.f6.
5
Putting rectal 5-aminosalicylic acid in its place: the role in distal ulcerative colitis.
Am J Gastroenterol. 2000 Jul;95(7):1628-36. doi: 10.1111/j.1572-0241.2000.02180.x.
6
Prevalence of nonadherence with maintenance mesalamine in quiescent ulcerative colitis.
Am J Gastroenterol. 2001 Oct;96(10):2929-33. doi: 10.1111/j.1572-0241.2001.04683.x.
8
Review article: evolving concepts in treatment and disease modification in ulcerative colitis.
Aliment Pharmacol Ther. 2008 Mar;27 Suppl 1:15-21. doi: 10.1111/j.1365-2036.2008.03606.x.
10
Reformulation of an aminosalicylate: an example of the importance of pill burden on medical compliance rates.
Methods Find Exp Clin Pharmacol. 2009 Jan-Feb;31(1):41-6. doi: 10.1358/mf.2009.31.1.1328635.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验