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探索患者报告变量和临床医生评估变量对预测腰痛患者工作状态的作用。

Exploring the contribution of patient-reported and clinician based variables for the prediction of low back work status.

作者信息

Heymans Martijn W, Ford Jon J, McMeeken Joan M, Chan Alexander, de Vet Henrica C W, van Mechelen Willem

机构信息

Body@Work, Research Center Physical Activity, Work and Health, TNO-VUmc, Amsterdam, The Netherlands.

出版信息

J Occup Rehabil. 2007 Sep;17(3):383-97. doi: 10.1007/s10926-007-9084-1. Epub 2007 Jun 15.

Abstract

BACKGROUND

Successful management of workers on sick leave due to low back pain by the general physician and physiotherapist depends on reliable prognostic information on the course of low back pain and work resumption.

METHODS

Retrospective cohort study in 194 patients who were compensated because of chronic low back pain and who were treated by a physiotherapy functional restoration program. Patient-reported and clinician based prognostic indicators were assessed at baseline before patients entered the functional restoration program. We investigated the predictive value of these indicators on work status at 6 months. Relationships were studied using logistic regression analysis in a 2-step bootstrap modelling approach and a nomogram was developed. Discrimination and calibration of the nomogram was evaluated internally and the explained variation of the nomogram calculated.

RESULTS

Seventy percent of workers were back to work at 6 months. We found that including duration of complaints, functional disability, disc herniation and fear avoidance beliefs resulted in the "best" prognostic model. All these factors delayed work resumption. This model was used to construct a nomogram. The explained variation of the nomogram was 23.7%. Discrimination was estimated by the area under the receiver operating characteristic curve and was 0.76 and for calibration we used the slope estimate that was 0.91. The positive predictive values of the nomogram at different cut-off levels of predicted probability were good.

CONCLUSIONS

Knowledge of the predictive value of these indicators by physicians and physiotherapists will help to identify subgroups of patients and will thus enhance clinical decision-making.

摘要

背景

全科医生和物理治疗师对因腰痛而休病假的工人进行成功管理,取决于有关腰痛病程和恢复工作的可靠预后信息。

方法

对194例因慢性腰痛获得补偿并接受物理治疗功能恢复计划治疗的患者进行回顾性队列研究。在患者进入功能恢复计划之前,于基线时评估患者报告的和基于临床医生的预后指标。我们调查了这些指标对6个月时工作状态的预测价值。使用两步法自助建模方法中的逻辑回归分析研究关系,并绘制列线图。对列线图的区分度和校准进行内部评估,并计算列线图的解释变异度。

结果

70%的工人在6个月时恢复工作。我们发现,纳入疼痛持续时间、功能障碍、椎间盘突出和恐惧回避信念可得出“最佳”预后模型。所有这些因素都延迟了恢复工作的时间。该模型用于构建列线图。列线图的解释变异度为23.7%。通过受试者操作特征曲线下面积估计区分度,为0.76,对于校准,我们使用斜率估计值,为0.91。列线图在不同预测概率截断水平下的阳性预测值良好。

结论

医生和物理治疗师了解这些指标的预测价值,将有助于识别患者亚组,从而加强临床决策。

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