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先天性心脏病女性的妊娠结局:文献综述

Outcome of pregnancy in women with congenital heart disease: a literature review.

作者信息

Drenthen Willem, Pieper Petronella G, Roos-Hesselink Jolien W, van Lottum Willem A, Voors Adriaan A, Mulder Barbara J M, van Dijk Arie P J, Vliegen Hubert W, Yap Sing C, Moons Philip, Ebels Tjark, van Veldhuisen Dirk J

机构信息

Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands.

出版信息

J Am Coll Cardiol. 2007 Jun 19;49(24):2303-11. doi: 10.1016/j.jacc.2007.03.027. Epub 2007 Jun 4.

Abstract

A search of peer-reviewed literature was conducted to identify reports that provide data on complications associated with pregnancy in women with structural congenital heart disease (CHD). This review describes the outcome of 2,491 pregnancies, including 377 miscarriages (15%) and 114 elective abortions (5%). Important cardiac complications were seen in 11% of the pregnancies. Obstetric complications do not appear to be more prevalent. In complex CHD, premature delivery rates are high, and more children are small for gestational age. The offspring mortality was high throughout the spectrum and was related to the relatively high rate of premature delivery and recurrence of CHD.

摘要

我们检索了同行评审文献,以找出提供有关结构性先天性心脏病(CHD)女性妊娠相关并发症数据的报告。本综述描述了2491例妊娠的结局,包括377例流产(15%)和114例选择性堕胎(5%)。11%的妊娠出现了重要的心脏并发症。产科并发症似乎并不更普遍。在复杂先天性心脏病中,早产率很高,且更多儿童小于孕周。在整个范围内,后代死亡率都很高,并且与相对较高的早产率和先天性心脏病复发率有关。

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