Thonneau P, Marchand S, Tallec A, Ferial M L, Ducot B, Lansac J, Lopes P, Tabaste J M, Spira A
INSERM (Institut National de la Santé et de la Recherche Médicale), Unité de Santé publique-Epidémiologie-Reproduction humaine, Centre Hospitalier Universitaire de Bicêtre France.
Hum Reprod. 1991 Jul;6(6):811-6. doi: 10.1093/oxfordjournals.humrep.a137433.
To estimate the prevalence and main causes of infertility, a multicentre survey was conducted over 1 year (July 1988-June 1989) in three regions of France. All the 1686 couples in these regions, who consulted a practitioner for primary or secondary infertility during this period, were included in the investigation. The prevalence rate of infertility was found to be 14.1%, indicating that one woman out of seven in France will consult a doctor for an infertility problem during her reproductive life. The main causes of female infertility were ovulation disorders (32%) and tubal damage (26%), and of male infertility oligo-terato-asthenozoospermia (21%), asthenozoospermia (17%), teratozoospermia (10%) and azoospermia (9%). Infertility was also found to be caused by disorders in both the male and female partners together; thus in 39% of cases both the man and woman presented with disorders. The woman alone was responsible for infertility in one-third of cases and the man alone in one-fifth. Unexplained infertility was found in 8% of the couples surveyed.
为了估算不孕症的患病率及主要病因,于1988年7月至1989年6月的1年时间里在法国三个地区开展了一项多中心调查。在此期间,这些地区向医生咨询原发性或继发性不孕症的1686对夫妇均纳入调查。结果发现不孕症的患病率为14.1%,这表明法国每七名女性中就有一人在其生育期会因不孕症问题就医。女性不孕症的主要病因是排卵障碍(32%)和输卵管损伤(26%),男性不孕症的主要病因是少弱畸精子症(21%)、弱精子症(17%)、畸精子症(10%)和无精子症(9%)。还发现不孕症是由男女双方共同的病症引起的;因此,在39%的病例中,男性和女性都存在病症。仅女性导致不孕症的病例占三分之一,仅男性导致不孕症的病例占五分之一。在接受调查的夫妇中,8%患有不明原因的不孕症。