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[神经白塞病:一组患者的磁共振成像研究]

[Neuro-Behçet: MR study of a group of patients].

作者信息

Ramos Cristina, Sá Goreti, Tedim Cruz Vítor, Lopes Alexandra, Xavier João, Cruz Romeu

机构信息

Serviço de Neurorradiologia, Hospital Geral de Santo António, Porto, Portugal.

出版信息

Acta Med Port. 2006 Nov-Dec;19(6):494-8. Epub 2007 May 14.

Abstract

Behçet's disease is a chronic inflammatory, multisystemic disease of unknown aetiology. Central nervous system involvement occurs in a variable proportion of cases (4 to 49%) and is due to intracranial hypertension secondary to dural sinus thrombosis, inflammatory parenquimal lesions or recurrent meningoencephalitis. We reviewed 12 patients, 7 men and 5 women, aged between 27 to 40 years at the time of diagnosis. Neurological manifestations were secondary to parenquimal lesions in 7 patients, meningoencephalitis in 3 patients (including one with extensive medullary lesion) and dural sinus thrombosis in 2. Magnetic Resonance (MR) findings in Neuro-Behçet are non-specific. Nevertheless, MR has a role in characterizing brain lesions topography, helping in the diagnosis and in the follow-up of these patients.

摘要

白塞病是一种病因不明的慢性炎症性多系统疾病。中枢神经系统受累在不同比例的病例中出现(4%至49%),其原因是硬脑膜窦血栓形成、炎症性实质病变或复发性脑膜脑炎继发的颅内高压。我们回顾了12例患者,其中7例男性,5例女性,诊断时年龄在27至40岁之间。7例患者的神经表现继发于实质病变,3例患者继发于脑膜脑炎(包括1例有广泛延髓病变的患者),2例患者继发于硬脑膜窦血栓形成。神经白塞病的磁共振(MR)表现不具有特异性。然而,MR在描述脑病变的部位、辅助诊断以及对这些患者的随访中具有作用。

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