Ramos Cristina, Sá Goreti, Tedim Cruz Vítor, Lopes Alexandra, Xavier João, Cruz Romeu
Serviço de Neurorradiologia, Hospital Geral de Santo António, Porto, Portugal.
Acta Med Port. 2006 Nov-Dec;19(6):494-8. Epub 2007 May 14.
Behçet's disease is a chronic inflammatory, multisystemic disease of unknown aetiology. Central nervous system involvement occurs in a variable proportion of cases (4 to 49%) and is due to intracranial hypertension secondary to dural sinus thrombosis, inflammatory parenquimal lesions or recurrent meningoencephalitis. We reviewed 12 patients, 7 men and 5 women, aged between 27 to 40 years at the time of diagnosis. Neurological manifestations were secondary to parenquimal lesions in 7 patients, meningoencephalitis in 3 patients (including one with extensive medullary lesion) and dural sinus thrombosis in 2. Magnetic Resonance (MR) findings in Neuro-Behçet are non-specific. Nevertheless, MR has a role in characterizing brain lesions topography, helping in the diagnosis and in the follow-up of these patients.
白塞病是一种病因不明的慢性炎症性多系统疾病。中枢神经系统受累在不同比例的病例中出现(4%至49%),其原因是硬脑膜窦血栓形成、炎症性实质病变或复发性脑膜脑炎继发的颅内高压。我们回顾了12例患者,其中7例男性,5例女性,诊断时年龄在27至40岁之间。7例患者的神经表现继发于实质病变,3例患者继发于脑膜脑炎(包括1例有广泛延髓病变的患者),2例患者继发于硬脑膜窦血栓形成。神经白塞病的磁共振(MR)表现不具有特异性。然而,MR在描述脑病变的部位、辅助诊断以及对这些患者的随访中具有作用。