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基于联合熵的短期心跳序列非线性动力学复杂性分析

[Nonlinear dynamical complexity analysis of short-term heartbeat series using joint entropy].

作者信息

Li Jin, Ning Xinbao, Ma Oianli

机构信息

State Key Laboratory Engineering, Nanjing University, Nanjing 210093, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2007 Apr;24(2):285-9.

Abstract

In this paper is reported a method using joint entropy to analyze the nonlinear dynamical complexity of short-term heart rate variability(HRV) signal. This method can effectively pick up dynamical information from the short-term heartbeat time series, reflect the dynamical complexity of heart rate variability, and so improve the quality of being covenient in clinical application. At first, the joint entropy method is demonstrated by applying it to the low-dimensional nonlinear deterministic systems such as logistic map and henon map. Then, the proposition is applied to the short-term heartbeat time series. The result shows that the method could robustly discriminate the patterns generated from healthy and pathologic states, as well as aging. Furthermore, the authors point out that decreased nonlinear dynamical complexity in the heartbeat time series with physiological aging and pathologic states is probably due to self-adjusting ability depression with aging and disease. At last, using the joint entropy method,the authors uncover nonrandom patterns in the ventricular response to atrial fibrillation.

摘要

本文报道了一种利用联合熵分析短期心率变异性(HRV)信号非线性动力学复杂性的方法。该方法能有效提取短期心跳时间序列中的动力学信息,反映心率变异性的动力学复杂性,从而提高其在临床应用中的便利性。首先,通过将联合熵方法应用于逻辑斯谛映射和亨农映射等低维非线性确定性系统来进行演示。然后,将该方法应用于短期心跳时间序列。结果表明,该方法能够稳健地区分健康状态、病理状态以及衰老状态所产生的模式。此外,作者指出,随着生理衰老和病理状态的出现,心跳时间序列中的非线性动力学复杂性降低可能是由于衰老和疾病导致的自我调节能力下降。最后,作者利用联合熵方法揭示了心室对心房颤动反应中的非随机模式。

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