[用于梅毒PCR检测的临床标本]
[Clinical specimens for PCR detection of syphilis].
作者信息
Woznicová V, Votava M, Flasarová M
机构信息
Mikrobiologický ústav LF MU a FN u sv. Anny v Brne, Brno.
出版信息
Epidemiol Mikrobiol Imunol. 2007 Apr;56(2):66-71.
A review is presented of types of clinical specimens used for diagnosis of syphilis by polymerase chain reaction. PCR is a routine method for detection of T. pallidum in swabs of chancres and primary and secondary syphilis mucocutaneous lesions. Whole blood, cerebrospinal fluid, amniotic fluid, aspirate and biopsy specimens, and paraffin-embedded tissues can also be tested by PCR for T. pallidum. However, further research on PCR detection sensitivity at various stages of syphilis is needed before these specimens are used in clinical practice.
本文综述了用于通过聚合酶链反应诊断梅毒的临床标本类型。聚合酶链反应（PCR）是检测梅毒螺旋体在硬下疳拭子以及一期和二期梅毒黏膜皮肤损害中的常规方法。全血、脑脊液、羊水、抽吸物和活检标本以及石蜡包埋组织也可通过PCR检测梅毒螺旋体。然而，在将这些标本用于临床实践之前，需要对梅毒各阶段的PCR检测灵敏度进行进一步研究。
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