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精索原发性骨肉瘤:病例报告及文献复习

Primary osteosarcoma of the spermatic cord: case report and literature review.

作者信息

Stella Mattia, Di Somma Carmine, Solari Nicola, Nozza Paolo, Meszaros Paolo, Weiss Annalisa, Bertoglio Sergio

机构信息

Department of Surgical Oncology, National Institute for Cancer Research IST, Genoa, Italy.

出版信息

Anticancer Res. 2007 May-Jun;27(3B):1605-8.

Abstract

Primary osteosarcoma of the spermatic cord is a rare tumour with few mentions in the literature. A 59-year-old man presented with a large painless left inguinal and scrotal mass. The patient underwent excision of the mass, which arose from the spermatic cord. A left high dissection of the spermatic cord and radical orchiectomy due to associated atrophy of the left testicle were performed. Pathological findings were suggestive of spermatic cord osteosarcoma. The patient died eleven years later of metastatic lung disease. Spermatic cord osteosarcoma is an uncommon neoplasm and its preoperative diagnosis is very difficult. Any palpable suspicious mass of the cord should be investigated with ultrasonography before excision; CT scan and magnetic resonance imaging may be helpful in defining preoperative diagnosis and the extension of the mass into the neighbouring tissues. Surgical treatment of spermatic cord sarcomas in adults is via a radical orchiectomy with high dissection of the spermatic cord and en bloc excision of involved neighbouring tissues; overall 5- and 10-year survival rates are reported in the literature to be 75% and 55%, respectively.

摘要

精索原发性骨肉瘤是一种罕见的肿瘤,在文献中鲜有提及。一名59岁男性患者出现左侧腹股沟和阴囊无痛性大包块。患者接受了源于精索的包块切除术。由于左侧睾丸伴有萎缩,进行了左侧精索高位解剖及根治性睾丸切除术。病理结果提示为精索骨肉瘤。该患者11年后死于肺转移。精索骨肉瘤是一种罕见肿瘤,术前诊断非常困难。任何可触及的可疑精索肿块在切除前均应行超声检查;CT扫描和磁共振成像可能有助于明确术前诊断及肿块向邻近组织的浸润范围。成人精索肉瘤的手术治疗是行根治性睾丸切除术并高位解剖精索,整块切除受累的邻近组织;文献报道总体5年和10年生存率分别为75%和55%。

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