Rozova K V, Trepats'ka T V, Horiana L H, Dubova M H, Man'kovs'ka I M
Fiziol Zh (1994). 2007;53(2):8-15.
Organ-specific alterations of ultrastructure and morphofunctional condition in different organism's tissues, which could evidence of the genetic factors inclusion under the development of different hypoxic condition in organism, were investigated. The dates obtained indicated the marked organ-specific "structure" reaction of tissues, cells and organelles under various exogenous influences. Such reactions confirm the presence of different genes expression which account for ultrastructure alterations; its activity is determined by a type, intensity, duration of influence as well as organ belonging. Ultrastructural alterations are mainly determined by tissue and cell factors but not by genetically determined system reactions; it is confirmed by various reactions on external factors in animal tissues with different genetically determined oxygen consumption level or genetically determined adaptation to middle-altitude conditions.
研究了不同生物体组织中超微结构和形态功能状态的器官特异性改变,这些改变可证明在生物体不同缺氧条件发展过程中遗传因素的参与。所获得的数据表明,在各种外源性影响下,组织、细胞和细胞器存在明显的器官特异性“结构”反应。这些反应证实了不同基因表达的存在,这些基因表达导致了超微结构的改变;其活性由影响的类型、强度、持续时间以及所属器官决定。超微结构的改变主要由组织和细胞因素决定,而非由基因决定的系统反应决定;这在具有不同基因决定的耗氧量水平或基因决定的对中等海拔条件适应能力的动物组织对外界因素的各种反应中得到了证实。