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与标准社区心理健康团队中首次精神病发作的常规治疗相比,精神病早期干预服务的三年结果。初步结果。

Three year outcomes of an early intervention for psychosis service as compared with treatment as usual for first psychotic episodes in a standard community mental health team. Preliminary results.

作者信息

Agius Mark, Shah Samir, Ramkisson Roshelle, Murphy Suzanne, Zaman Rashid

机构信息

Bedfordshire Centre For Mental Health Research in Association with the University of Cambridge Weller Wing Bedford Hospital, Bedford, England.

出版信息

Psychiatr Danub. 2007 Jun;19(1-2):10-9.

Abstract

Forty patients who had been treated for three years in an ad-hoc, assertive treatment team for patients who had suffered a first psychotic episode were compared to forty patients who had been followed up after a first psychotic episode in a community mental health team. All patients had suffered a first or early psychotic episode. The main differences between the two teams was that the ad-hoc team was assertive in its approach, offered more structured psycho-education, relapse prevention and psycho-social interventions, and had a policy of using atypical anti-psychotics at the lowest effective dose. There were many differences in outcome measures at the end of three years between the two groups. The EI patients are more likely to be taking medication at the end of three years. They are more compliant with medication. They are more likely to be prescribed atypical medication. The EI patients are more likely to have returned to work or education. The EI patients are more likely to remain living with their families. They are less likely to suffer depression to the extent of requiring anti-depressants. They appear to commit less suicide attempts. The patients in the EI service also appear to be less likely to suffer relapse and re-hospitalisation, and are less likely to have involuntary admission to hospital. They have systematic relapse prevention plans based on early warning signs. They and their families receive more psycho-education. These indications suggest that the EI patients are at the end of three years better able to manage their illness/vulnerability on their own than the CMHT patients. More patients in the EI group stopped using illicit drugs than in the CMHT group. All the above changes were statistically significant except for the number of patients who stopped using illicit drugs. In this case it is believed that the sample size was too small to demonstrate significance. These results suggest that an ad-hoc early intervention team is more effective than standard community mental health team in treating psychotic illness.

摘要

四十名在一个专门为首次出现精神病发作的患者设立的积极治疗团队中接受了三年治疗的患者,与四十名在社区精神卫生团队中首次出现精神病发作后接受随访的患者进行了比较。所有患者均经历过首次或早期精神病发作。两个团队之间的主要差异在于,专门治疗团队的治疗方法积极主动,提供了更具结构性的心理教育、复发预防和心理社会干预措施,并且有以最低有效剂量使用非典型抗精神病药物的政策。两组患者在三年结束时的结局指标存在许多差异。接受积极干预(EI)的患者在三年结束时更有可能正在服药。他们对药物治疗的依从性更高。他们更有可能被开具非典型药物。接受积极干预的患者更有可能重返工作或接受教育。接受积极干预的患者更有可能继续与家人同住。他们因抑郁而需要服用抗抑郁药的可能性较小。他们似乎尝试自杀的次数较少。接受积极干预服务的患者似乎也不太可能复发和再次住院,并且不太可能被非自愿收治入院。他们有基于早期预警信号的系统复发预防计划。他们及其家人接受了更多的心理教育。这些迹象表明,在三年结束时,接受积极干预的患者比接受社区精神卫生团队治疗(CMHT)的患者更有能力自行管理自己的疾病/脆弱性。与社区精神卫生团队组相比,积极干预组中更多患者停止使用非法药物。除了停止使用非法药物的患者数量外,上述所有变化均具有统计学意义。在这种情况下,据信样本量太小,无法显示出显著性。这些结果表明,一个专门的早期干预团队在治疗精神病性疾病方面比标准的社区精神卫生团队更有效。

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