Bazin Pierre-Louis, Cuzzocreo Jennifer L, Yassa Michael A, Gandler William, McAuliffe Matthew J, Bassett Susan S, Pham Dzung L
Laboratory of Medical Image Computing, Neuroradiology Division, Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD 21218, USA.
J Neurosci Methods. 2007 Sep 15;165(1):111-21. doi: 10.1016/j.jneumeth.2007.05.024. Epub 2007 May 29.
We describe a new collection of publicly available software tools for performing quantitative neuroimage analysis. The tools perform semi-automatic brain extraction, tissue classification, Talairach alignment, and atlas-based measurements within a user-friendly graphical environment. They are implemented as plug-ins for MIPAV, a freely available medical image processing software package from the National Institutes of Health. Because the plug-ins and MIPAV are implemented in Java, both can be utilized on nearly any operating system platform. In addition to the software plug-ins, we have also released a digital version of the Talairach atlas that can be used to perform regional volumetric analyses. Several studies are conducted applying the new tools to simulated and real neuroimaging data sets.
我们描述了一组新的公开可用软件工具,用于进行定量神经影像分析。这些工具在用户友好的图形环境中执行半自动脑提取、组织分类、Talairach配准和基于图谱的测量。它们被实现为MIPAV的插件,MIPAV是美国国立卫生研究院免费提供的医学图像处理软件包。由于插件和MIPAV是用Java实现的,两者几乎可以在任何操作系统平台上使用。除了软件插件,我们还发布了Talairach图谱的数字版本,可用于进行区域体积分析。我们进行了几项研究,将这些新工具应用于模拟和真实的神经影像数据集。