Antunes N T, Tavío M M, Assunção P, Rosales R S, Poveda C, de la Fé C, Gil M C, Poveda J B
Unidad de Epidemiologi a y Medicina Preventiva, Instituto Universitario de Sanidad Animal (IUSA), Universidad de Las Palmas de Gran Canaria, Arucas, Spain.
Vet J. 2008 Sep;177(3):436-8. doi: 10.1016/j.tvjl.2007.05.008. Epub 2007 Jul 2.
In order to determine how widespread antibiotic resistance has become to standard treatments, the in vitro susceptibilities of 28 Mycoplasma agalactiae Spanish field isolates to 16 antimicrobial agents were determined using a broth microdilution method. The most effective antimicrobials based on minimum inhibitory concentration (MIC)(90) values were fluoroquinolones, tetracyclines and macrolides. Two strains were tetracycline resistant. Streptomycin, erythromycin and nalidixic acid resistance was observed in all strains.
为了确定对标准治疗方法的抗生素耐药性已扩散到何种程度,使用肉汤微量稀释法测定了28株西班牙无乳支原体田间分离株对16种抗菌剂的体外敏感性。基于最低抑菌浓度(MIC)(90)值,最有效的抗菌剂是氟喹诺酮类、四环素类和大环内酯类。有两株菌株对四环素耐药。在所有菌株中均观察到对链霉素、红霉素和萘啶酸的耐药性。