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由源自特发性左心室动脉瘤的室性心动过速非接触式标测引导的射频导管消融术

Radiofrequency catheter ablation guided by noncontact mapping of ventricular tachycardia originating from an idiopathic left ventricular aneurysm.

作者信息

Santamaria Matteo, Cireddu Manuela, Riva Stefania, Trevisi Nicola, Della Bella Paolo

机构信息

Cardiovascular Department, Catholic University of the Sacred Heart, Largo A. Gemelli 1, 86100 Campobasso, Italy.

出版信息

J Interv Card Electrophysiol. 2007 Jun;19(1):49-53. doi: 10.1007/s10840-007-9132-y. Epub 2007 Jun 29.

Abstract

Idiopathic left ventricular aneurysm and diverticulum is known to be an arrhythmogenic substrate associated to ventricular tachyarrhythmias, generally based on a reentry mechanism. A case of a young woman affected by a monomorphic ventricular tachycardia, refractory to medical treatment, originating from an aneurysm of the membranous interventricular septum is reported. The left ventricular aneurysm was well characterized by multislice computed tomography and left ventricular angiography. Because of the nonsustained and poorly tolerated nature of the target arrhythmia, a noncontact mapping system was used to guide radiofrequency catheter ablation, allowing the elaboration of a three-dimensional activation map of the left ventricle on the basis of a ventricular tachycardia single beat. The procedure was acutely successful, and the patient remained free of ventricular tachycardia recurrences without antiarrhythmic drugs during a subsequent 6-month follow-up period. This is the first report of a successful radiofrequency catheter ablation guided by noncontact mapping system of a ventricular tachycardia originating from an idiopathic left ventricular aneurysm. This nonfluoroscopic mapping method allows a reliable reconstruction of the spatial relationships between the left ventricular main cavity and the aneurysm and can be safely and effectively used to map the ventricular tachycardia and guide the ablation procedure, particularly when conventional mapping is not indicated or not effective because of nonsustained or not-tolerated characters of ventricular tachycardia.

摘要

特发性左心室动脉瘤和憩室被认为是与室性快速心律失常相关的致心律失常基质,通常基于折返机制。本文报道了一例年轻女性患者,其患有单形性室性心动过速,药物治疗无效,该室性心动过速起源于膜性室间隔动脉瘤。多层计算机断层扫描和左心室血管造影对左心室动脉瘤进行了很好的特征描述。由于目标心律失常的非持续性和耐受性差的特点,使用非接触式标测系统指导射频导管消融,基于室性心动过速单搏构建左心室三维激动图。该手术即刻成功,在随后6个月的随访期内,患者未使用抗心律失常药物,室性心动过速未复发。这是首例由非接触式标测系统指导成功进行射频导管消融治疗起源于特发性左心室动脉瘤的室性心动过速的报告。这种非荧光透视标测方法能够可靠地重建左心室主腔与动脉瘤之间的空间关系,并且可以安全有效地用于标测室性心动过速并指导消融手术,特别是当由于室性心动过速的非持续性或耐受性差而不适合或无效进行传统标测时。

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