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[骨折的绝对风险与世界卫生组织指南。绝经后女性预防骨折药物的选择]

[Absolute risk for fracture and WHO guideline. Selection of drugs for the prevention of fractures in postmenopausal women].

作者信息

Gorai Itsuo

机构信息

International University of Health and Welfare Atami Hospital, Department of Obstetrics and Gynecology.

出版信息

Clin Calcium. 2007 Jul;17(7):1090-6.

Abstract

It is crucial to select drugs for the prevention of fracture in postmenopausal osteoporosis. In early postmenopausal women with climacteric symptoms hormone replacement therapy (HRT) would be a first choice. Selective estrogen receptor modulator (SERM) could be prescribed in postmenopausal women who had been treated with HRT. Osteoporotic women with high risk of future fractures would be administered bisphosphonates. It is highly recommended that the doctor's decision on the drug (s) for each patient with osteoporosis could be made after obtaining the informed consent.

摘要

选择预防绝经后骨质疏松症的药物至关重要。对于有更年期症状的绝经早期女性,激素替代疗法(HRT)将是首选。对于接受过HRT治疗的绝经后女性,可以开选择性雌激素受体调节剂(SERM)。未来骨折风险高的骨质疏松症女性将使用双膦酸盐。强烈建议医生在获得知情同意后,为每位骨质疏松症患者做出药物选择的决定。

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