Sutton M A, Ke X, Lessner S M, Goldbach M, Yost M, Zhao F, Schreier H W
Department of Mechanical Engineering, University of South Carolina, Columbia, South Carolina 29208, USA.
J Biomed Mater Res A. 2008 Jan;84(1):178-90. doi: 10.1002/jbm.a.31268.
A stereomicroscope system is adapted to make accurate, quantitative displacement, and strain field measurements with microscale spatial resolution and nanoscale displacement resolution on mouse carotid arteries. To perform accurate and reliable calibration for these systems, a two-step calibration process is proposed and demonstrated using a modification to recently published procedures. Experimental results demonstrate that the microscope system with three-dimensional digital image correlation (3D-DIC) successfully measures the full 3D displacement and surface strain fields at the microscale during pressure cycling of 0.40-mm-diameter mouse arteries, confirming that the technique can be used to quantify changes in local biomechanical response which may result from variations in extracellular matrix composition, with the goal of quantifying properties of the vessel.
立体显微镜系统适用于在小鼠颈动脉上以微米级空间分辨率和纳米级位移分辨率进行精确的定量位移和应变场测量。为了对这些系统进行准确可靠的校准，我们提出并展示了一种两步校准过程，该过程是对最近发表的程序进行了修改。实验结果表明，具有三维数字图像相关技术（3D-DIC）的显微镜系统在直径为0.40毫米的小鼠动脉压力循环过程中成功地在微观尺度上测量了完整的三维位移和表面应变场，证实了该技术可用于量化可能由细胞外基质组成变化引起的局部生物力学响应变化，目标是量化血管的特性。
Zotero 插件