Li Ang, Kwong Richard, Cerussi Albert, Merritt Sean, Hayakawa Carole, Tromberg Bruce
Beckman Laser Institute and Medical Clinic, University of California-Irvine, 92612, USA.
Appl Opt. 2007 Jul 20;46(21):4828-33. doi: 10.1364/ao.46.004828.
We report the recovery of broadband (650-1000 nm) diffuse optical absorption and reduced scattering spectra stratified by layer in a two-layer phantom. The broadband optical properties of the phantom featured top and bottom layers designed to simulate adipose and muscle, respectively. The absolute value and dynamic variation of chromophore concentrations in both layers (top layer thickness greater than 5 mm) were calculated with an average 10% error and 3% error, respectively. In addition to spectra, the algorithm recovers the top layer thickness up to 12 mm within 10% error. It is insensitive to initial guesses of both layers' optical properties as long as the layer thickness initial guess is within +/-2 mm.
我们报告了在双层模型中按层分层恢复的宽带（650 - 1000纳米）漫射光吸收和减少散射光谱。该模型的宽带光学特性具有分别设计用于模拟脂肪和肌肉的顶层和底层。两层（顶层厚度大于5毫米）中发色团浓度的绝对值和动态变化分别以平均10%的误差和3%的误差计算得出。除了光谱外，该算法还能在10%的误差范围内恢复高达12毫米的顶层厚度。只要层厚度的初始猜测在±2毫米范围内，它对两层光学特性的初始猜测不敏感。
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