Onur Rahmi, Singla Ajay, Kobashi Kathleen C
Department of Urology, Firat University, Elazig, Turkey,
Int Urol Nephrol. 2008;40(1):45-9. doi: 10.1007/s11255-007-9210-1. Epub 2007 Jul 3.
To evaluate the efficacy of pubovaginal sling using human cadaveric dermis processed by solvent dehydration and compare results to those of another group in which autograft rectus fascia was used.
The efficacy of autologous rectus fascia (group 1, n=25) or solvent-dehydrated cadaveric dermis (group 2, n=24) for pubovaginal sling were compared in women with stress urinary incontinence (SUI). Surgical outcome, patient satisfaction and quality of life was assessed by the urogenital distress inventory (UDI-6) and the incontinence impact questionnaire (IIQ-7).
Mean follow-up for patients in group 1 and group 2 were 18 and 13 months, respectively. Our questionnaire-based assessment revealed that SUI was either cured or improved in a total of 21 (84%) patients in group 1 and 19 (79%) patients in group 2. No statistically significant difference was found for the overall success (P<0.05) and no major complications were encountered in both groups.
Use of allograft dermis as an alternative to autologous rectus fascia for pubovaginal sling had comparable improvement in patient satisfaction and quality of life at intermediate term.
评估使用经溶剂脱水处理的人尸体真皮进行耻骨后阴道悬吊术的疗效,并将结果与使用自体腹直肌筋膜的另一组进行比较。
在压力性尿失禁(SUI)女性患者中,比较自体腹直肌筋膜(第1组,n = 25)或经溶剂脱水的尸体真皮(第2组,n = 24)用于耻骨后阴道悬吊术的疗效。通过泌尿生殖系统困扰量表(UDI - 6)和尿失禁影响问卷(IIQ - 7)评估手术结果、患者满意度和生活质量。
第1组和第2组患者的平均随访时间分别为18个月和13个月。我们基于问卷的评估显示,第1组共有21例(84%)患者的SUI得到治愈或改善,第2组有19例(79%)患者。总体成功率无统计学显著差异(P < 0.05),两组均未出现重大并发症。
在中期,使用同种异体真皮替代自体腹直肌筋膜进行耻骨后阴道悬吊术在患者满意度和生活质量方面有相似的改善。