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一项针对类风湿性关节炎患者的集体教育项目的效果:一项为期12个月的前瞻性随机对照试验。

Effect of a collective educational program for patients with rheumatoid arthritis: a prospective 12-month randomized controlled trial.

作者信息

Giraudet-Le Quintrec Janine-Sophie, Mayoux-Benhamou Anne, Ravaud Philippe, Champion Karine, Dernis Emmanuelle, Zerkak Djamila, Ouslimani Amel, Courpied Jean-Pierre, Revel Michel, Kahan André, Dougados Maxime

机构信息

AP-HP, Hôpital Cochin, Université René-Descartes, Faculté de Médecine, Paris, France.

出版信息

J Rheumatol. 2007 Aug;34(8):1684-91. Epub 2007 Jun 15.

Abstract

OBJECTIVE

To evaluate the effect on health and functional status of an 8-week group-education program for rheumatoid arthritis (RA) in addition to usual medical care.

METHODS

All consecutive inpatients and outpatients with RA (ACR criteria) were asked to participate in this randomized, prospective, controlled trial. The educational intervention consisted of 8 weekly ambulatory sessions, each lasting 6 hours. Followup was undertaken after 1 year. The primary criterion for judging effectiveness was the Health Assessment Questionnaire (HAQ) score; secondary criteria consisted of coping, medical knowledge, patient global satisfaction, and quality of life scores before the intervention and after 1 year.

RESULTS

We asked 1242 inpatients and outpatients to participate in the study: 208 (16.75%) agreed (104 in each group). At baseline, there was no statistically significant difference between the 2 groups. After 1 year, no statistically significant difference was observed between the 2 groups in change in HAQ score: -0.04 +/- 0.46 (education group) vs -0.06 +/- 0.47 (control group) (p = 0.79). Statistically significant differences were found in 3 domains: patient coping (-1.22 +/- 5.55 vs -0.22 +/- 3.81; p = 0.03), knowledge (3.42 +/- 4.73 vs 0.73 +/- 3.78; p < 0.0001), and satisfaction (10.07 +/- 11.70 vs 5.72 +/- 13.77; p = 0.02), all of which were better for the group attending the education sessions.

CONCLUSION

Despite improvements in patient coping, knowledge, and satisfaction, the education program was not found to be effective at 1 year. There may have been methodological problems relating to the sensitivity of questionnaires and patient selection, and tailored educational interventions should be considered.

摘要

目的

评估在常规医疗护理基础上,为期8周的类风湿关节炎(RA)团体教育项目对健康和功能状态的影响。

方法

所有符合美国风湿病学会(ACR)标准的连续住院和门诊RA患者均被邀请参与这项随机、前瞻性对照试验。教育干预包括8次每周一次的门诊课程,每次持续6小时。1年后进行随访。判断有效性的主要标准是健康评估问卷(HAQ)评分;次要标准包括干预前及1年后的应对能力、医学知识、患者总体满意度和生活质量评分。

结果

我们邀请了1242名住院和门诊患者参与研究:208名(16.75%)同意参与(每组104名)。基线时,两组之间无统计学显著差异。1年后,两组在HAQ评分变化方面未观察到统计学显著差异:-0.04±0.46(教育组)对比-0.06±0.47(对照组)(p = 0.79)。在3个领域发现了统计学显著差异:患者应对能力(-1.22±5.55对比-0.22±3.81;p = 0.03)、知识(3.42±4.73对比0.73±3.78;p < 0.0001)和满意度(10.07±11.70对比5.72±13.77;p = 0.02),所有这些方面教育组均表现更好。

结论

尽管患者在应对能力、知识和满意度方面有所改善,但该教育项目在1年后未被发现有效。可能存在与问卷敏感性和患者选择相关的方法学问题,应考虑量身定制的教育干预措施。

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