POEMS综合征：自体外周血干细胞移植成功后复发
POEMS syndrome: relapse after successful autologous peripheral blood stem cell transplantation.
作者信息
Giglia F, Chiapparini L, Fariselli L, Barbui T, Ciano C, Scarlato M, Pareyson D
机构信息
Division of Biochemistry and Genetics, IRCCS Foundation, C. Besta Neurological Institute, Milan, Italy.
出版信息
Neuromuscul Disord. 2007 Dec;17(11-12):980-2. doi: 10.1016/j.nmd.2007.05.004. Epub 2007 Jul 3.
We report a patient with POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, Skin changes) treated with high dose chemotherapy and auto-Peripheral Blood Stem Cell Transplantation (auto-PBSCT) who had a very good response with complete clinical remission. Seven years later, she relapsed and a new sclerotic bone lesion was found. To our knowledge, this is the first POEMS syndrome relapse after successful auto-PBSCT.
我们报告了一名患有POEMS综合征（多发性神经病、器官肿大、内分泌病、单克隆丙种球蛋白病、皮肤改变）的患者，其接受了大剂量化疗和自体外周血干细胞移植（auto-PBSCT），并获得了非常好的反应，实现了完全临床缓解。七年后，她复发了，发现了一处新的硬化性骨病变。据我们所知，这是自体外周血干细胞移植成功后首次出现的POEMS综合征复发。
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