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通过不规则动脉狭窄的血流数学建模。

Mathematical modelling of flow through an irregular arterial stenosis.

作者信息

Johnston P R, Kilpatrick D

机构信息

Department of Medicine, University of Tasmania, Hobart, Australia.

出版信息

J Biomech. 1991;24(11):1069-77. doi: 10.1016/0021-9290(91)90023-g.

Abstract

A mathematical model of flow through an irregular arterial stenosis is developed. The model is two-dimensional and axi-symmetric with the stenosis outline obtained from a three-dimensional casting of a mildly stenosed artery. Agreement between modelled and experimental pressure drops (obtained from an axi-symmetric machined stenosis with the same profile) is excellent. Results are also obtained for a smooth stenosis model, similar to that used for most mathematical modelling studies. This model overestimates the pressure drop across the stenosis, as well as the wall shear stress and separation Reynolds number. Also, the smooth model predicts one instead of three recirculation zones present in the irregular model. The original stenosis is modified to increase the severity from 48 and 87% areal occlusion, while maintaining the same general shape. This has the effect of increasing the pressure drop by an order of magnitude and decreasing the number of recirculation zones to one, with a lower separation Reynolds number.

摘要

建立了一个通过不规则动脉狭窄处血流的数学模型。该模型是二维且轴对称的,狭窄轮廓取自轻度狭窄动脉的三维铸件。模拟的压降与实验压降(从具有相同轮廓的轴对称加工狭窄处获得)之间的一致性非常好。还得到了一个光滑狭窄模型的结果,该模型类似于大多数数学建模研究中使用的模型。这个模型高估了狭窄处的压降以及壁面剪应力和分离雷诺数。此外,光滑模型预测的是一个而不是不规则模型中存在的三个回流区。对原始狭窄进行修改,将面积阻塞率从48%增加到87%,同时保持大致相同的形状。这使得压降增加了一个数量级,回流区数量减少到一个,且分离雷诺数更低。

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