McArthur G J, Banwell M E, Cook M G, Powell B W
Department of Plastic and Reconstructive Surgery, St. George's Hospital NHS Trust, Blackshaw Road, Tooting London SW17 0QT, United Kingdom.
J Plast Reconstr Aesthet Surg. 2007;60(8):952-4. doi: 10.1016/j.bjps.2006.04.003. Epub 2006 Jun 27.
Melanocytic lesions of uncertain malignant potential (MUMP) is a term which is useful in identifying melanocytic tumours where the distinction between benign and malignant is a histological problem. Sentinel node biopsy is recognised to provide unmatched prognostic information in melanoma patients, but has recently been advocated for diagnostic purposes in MUMP. We present the case of a seven-year-old girl who presented with a six-month history of a changing pigmented lesion on her left upper arm. Excision biopsy not only showed a melanocytic lesion with some spitzoid features but also marked atypia making it appropriate to use the term MUMP. Sentinel node biopsy was undertaken. This case demonstrates that sentinel node biopsy can be performed safely in children. Given the low morbidity of the procedure we advocate that this technique should be considered in this difficult diagnostic situation to further the management of these patients.
具有不确定恶性潜能的黑素细胞病变(MUMP)是一个有助于识别黑素细胞肿瘤的术语,在这些肿瘤中,良恶性的区分是一个组织学问题。前哨淋巴结活检被认为能为黑色素瘤患者提供无与伦比的预后信息,但最近有人主张将其用于MUMP的诊断目的。我们报告一例七岁女孩,她左上臂有一个色素沉着病变,已有六个月变化史。切除活检不仅显示出具有一些梭形细胞特征的黑素细胞病变,还显示出明显的异型性,因此使用MUMP这一术语是合适的。于是进行了前哨淋巴结活检。该病例表明,前哨淋巴结活检在儿童中可以安全进行。鉴于该手术的低发病率,我们主张在这种困难的诊断情况下应考虑采用该技术,以进一步管理这些患者。