印度泰米尔纳德邦两个穆斯林群体中15个常染色体STR基因座的等位基因频率分布。
Allele frequency distribution for 15 autosomal STR loci in two Muslim populations of Tamilnadu, India.
作者信息
Eaaswarkhanth M, Roy Soma, Haque Ikramul
机构信息
National DNA Analysis Center, Directorate of Forensic Science, Central Forensic Science Laboratory, 30, Gorachand Road, Kolkata 700 014, India.
出版信息
Leg Med (Tokyo). 2007 Nov;9(6):332-5. doi: 10.1016/j.legalmed.2007.05.004. Epub 2007 Jul 5.
Allele frequencies of the 15 autosomal STR loci: D8S1179, D21S11, D7S820, CSF1PO, D19S433, vWA, TPOX, D18S51, D3S1358, THO1, D13S317, D16S539, D2S1338, D5S818, and FGA were determined in two endogamous Muslim populations (Dawoodi Bohra Muslims from Shiite Muslims and Sunni Muslims) residing in Tamilnadu, India. The Loci D7S820, CSF1PO, D19S433, vWA, TPOX, D13S317, D16S539, D5S818, and FGA in Dawoodi Bohra Muslims from Shiite Muslims, and CSF1PO, D19S433, TPOX, and D16S539 in Sunni Muslims were found to deviate significantly from Hardy-Weinberg equilibrium. The power of discrimination of the analyzed markers was found to be high for the populations, thereby facilitating the validation and efficiency of these STR markers in human identification.
在居住于印度泰米尔纳德邦的两个内婚制穆斯林群体（什叶派穆斯林中的达乌德·博拉穆斯林和逊尼派穆斯林）中，测定了15个常染色体STR基因座（D8S1179、D21S11、D7S820、CSF1PO、D19S433、vWA、TPOX、D18S51、D3S1358、THO1、D13S317、D16S539、D2S1338、D5S818和FGA）的等位基因频率。发现什叶派穆斯林中的达乌德·博拉穆斯林群体中的基因座D7S820、CSF1PO、D19S433、vWA、TPOX、D13S317、D16S539、D5S818和FGA，以及逊尼派穆斯林群体中的CSF1PO、D19S433、TPOX和D16S539显著偏离哈迪-温伯格平衡。对于这些群体，所分析标记的鉴别力较高，从而有助于这些STR标记在人类身份识别中的验证和有效性。
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