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欧洲过期产发生率的差异:是真实情况还是人为现象?

Variation in rates of postterm birth in Europe: reality or artefact?

作者信息

Zeitlin J, Blondel B, Alexander S, Bréart G

机构信息

INSERM, UMR S149, Epidemiological Research Unit on Perinatal and Women's Health, Paris, France.

出版信息

BJOG. 2007 Sep;114(9):1097-103. doi: 10.1111/j.1471-0528.2007.01328.x. Epub 2007 Jul 6.

Abstract

OBJECTIVE

To compare rates of postterm birth in Europe.

DESIGN

Analysis of data from vital statistics, birth registers, and national birth samples collected for the PERISTAT project.

SETTING

Thirteen European countries.

POPULATION

All live births or representative samples of births for the year 2000 or most recent year available.

METHODS

Comparison of national and regional rates of postterm birth. Other indicators (birthweight, deliveries with a non-spontaneous onset and mortality) were used to assess the validity of postterm rates.

MAIN OUTCOME MEASURES

The proportion of births at 42 completed weeks of gestation or later.

RESULTS

Postterm rates varied greatly, from 0.4% (Austria, Belgium) to over 7% (Denmark, Sweden) of births. Higher postterm rates were associated with a greater proportion of babies with birthweight 4500 g or more. Fetal and early neonatal mortality rates were higher among postterm births than among births at 40 weeks. Countries with higher proportions of births with a nonspontaneous onset of labour had lower postterm birth rates. The shapes of the gestational-age distributions at term varied. In some countries, there was a sharp cutoff in deliveries at 40 weeks, while elsewhere this occurred at 41 weeks.

CONCLUSIONS

These results suggest that practices for managing pregnancies continuing beyond term differ in Europe and raise questions about the health and other impacts in countries with markedly high or low postterm rates. Some variability in these rates may also be due to methods for determining gestational age, which has broader implications for international comparisons of gestational age, including rates of postterm and preterm births and small-for-gestational-age newborns.

摘要

目的

比较欧洲过期产的发生率。

设计

分析为围产期统计项目收集的生命统计数据、出生登记数据和全国出生样本数据。

地点

13个欧洲国家。

研究对象

2000年或可获取的最近一年的所有活产儿或具有代表性的出生样本。

方法

比较全国和地区过期产的发生率。使用其他指标(出生体重、非自然发动分娩和死亡率)评估过期产发生率的有效性。

主要观察指标

妊娠满42周及以后出生的比例。

结果

过期产发生率差异很大,从出生数的0.4%(奥地利、比利时)到超过7%(丹麦、瑞典)。过期产发生率较高与出生体重4500克及以上的婴儿比例较高相关。过期产儿的胎儿和早期新生儿死亡率高于40周出生的婴儿。非自然发动分娩比例较高的国家过期产发生率较低。足月时孕周分布的形状各不相同。在一些国家,40周时分娩数急剧减少,而在其他地方则在41周时出现这种情况。

结论

这些结果表明,欧洲对于超过足月妊娠的处理方法存在差异,并引发了关于过期产发生率显著高或低的国家中健康及其他影响的问题。这些发生率的一些差异也可能归因于确定孕周的方法,这对孕周的国际比较具有更广泛的影响,包括过期产和早产的发生率以及小于胎龄新生儿。

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