Stein J M, Schneider A R
Medizinische Klinik I-ZAFES, J. W. Goethe-Universität Frankfurt.
Z Gastroenterol. 2007 Jul;45(7):620-8. doi: 10.1055/s-2007-963045.
Small bowel bacterial overgrowth is a syndrome caused by an abnormal number of bacteria in the upper part of the small bowel and associated with a complex array of clinical symptoms, i. e., chronic diarrhoea, steatorrhoea, macrocytic anaemia, weight loss, and less commonly, protein-losing enteropathy. The most common underlying factors are small intestinal stagnation or dysmotility, intestinal obstruction, blind or afferent loops, and decreased gastric secretion. The treatment usually consists in the eradication of bacterial overgrowth with repeated courses of antimicrobials, correction of associated nutritional deficiencies and, when possible, correction of the underlying predisposing conditions.
小肠细菌过度生长是一种由小肠上段细菌数量异常引起的综合征,伴有一系列复杂的临床症状,即慢性腹泻、脂肪泻、大细胞性贫血、体重减轻,较少见的还有蛋白丢失性肠病。最常见的潜在因素是小肠淤滞或蠕动障碍、肠梗阻、盲袢或输入袢以及胃酸分泌减少。治疗通常包括用重复疗程的抗菌药物根除细菌过度生长、纠正相关的营养缺乏,以及尽可能纠正潜在的易感因素。