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颅面骨结核性和慢性化脓性骨髓炎:一项回顾性分析

Tubercular and chronic pyogenic osteomyelitis of cranio-facial bones: a retrospective analysis.

作者信息

Sethi A, Sethi D, Agarwal A K, Nigam S, Gupta A

机构信息

Department of ENT & Head and Neck Surgery, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.

出版信息

J Laryngol Otol. 2008 Aug;122(8):799-804. doi: 10.1017/S0022215107009541. Epub 2007 Jul 12.

Abstract

AIM

To analyse current trends in our population with respect to the presentation, diagnosis and management of tubercular and chronic pyogenic osteomyelitis of the cranio-facial bones.

DESIGN

Retrospective study.

SETTING

Tertiary healthcare centre.

PATIENTS AND METHODS

The study population comprised 14 patients with tubercular and chronic pyogenic osteomyelitis who were managed in the otorhinolaryngology department between May 2002 and December 2005.

RESULTS

Odontogenic infections, sinus infections and aural infections were the most commonly identified aetiological factors. Most of the patients presented with swelling, pain and discharging sinus. The diagnosis was established on the basis of clinical evaluation, radiological investigations and histopathological analysis, with six cases diagnosed with tubercular osteomyelitis and eight cases with chronic pyogenic osteomyelitis. All the patients were initially commenced on oral antibiotics, which were continued for two weeks in all cases with chronic pyogenic osteomyelitis. All the patients with pyogenic osteomyelitis underwent surgical management, with one patient requiring repeated surgical interventions. All the patients with tubercular osteomyelitis received anti-tubercular chemotherapy, with complete cure.

CONCLUSIONS

Osteomyelitis of the cranio-facial bones is an uncommon entity which requires a high index of clinical suspicion along with radiological and histopathological investigations in order to establish the diagnosis. Tubercular osteomyelitis is clinically and radiologically indistinguishable from pyogenic osteomyelitis, and the two conditions can be differentiated only on the basis of histopathological evaluation of involved tissue.

摘要

目的

分析我院在颅面骨结核性和慢性化脓性骨髓炎的临床表现、诊断及治疗方面的当前趋势。

设计

回顾性研究。

地点

三级医疗保健中心。

患者与方法

研究对象包括2002年5月至2005年12月间在耳鼻咽喉科接受治疗的14例结核性和慢性化脓性骨髓炎患者。

结果

牙源性感染、鼻窦感染和耳部感染是最常见的病因。大多数患者表现为肿胀、疼痛和鼻窦流脓。诊断基于临床评估、影像学检查和组织病理学分析,其中6例诊断为结核性骨髓炎,8例为慢性化脓性骨髓炎。所有患者最初均开始口服抗生素,慢性化脓性骨髓炎患者均持续使用两周。所有化脓性骨髓炎患者均接受了手术治疗,1例患者需要重复手术干预。所有结核性骨髓炎患者均接受抗结核化疗,最终完全治愈。

结论

颅面骨骨髓炎是一种罕见疾病,需要高度的临床怀疑,并结合影像学和组织病理学检查以确立诊断。结核性骨髓炎在临床和影像学上与化脓性骨髓炎难以区分,两者只能通过对受累组织的组织病理学评估来鉴别。

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