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模块化主动脉单侧髂动脉血管内支架型人工血管是治疗有症状的和破裂的肾下腹主动脉瘤的一种有用装置:一项多中心研究的一年结果

A modular aortouniiliac endovascular stent-graft is a useful device for the treatment of symptomatic and ruptured infrarenal abdominal aortic aneurysms: one-year results from a multicentre study.

作者信息

Hinchliffe R J, Braithwaite B D

机构信息

Department of Vascular and Endovascular Surgery, Nottingham University Hospital, Nottingham, UK.

出版信息

Eur J Vasc Endovasc Surg. 2007 Sep;34(3):291-8. doi: 10.1016/j.ejvs.2007.05.013. Epub 2007 Jul 10.

Abstract

INTRODUCTION

Endovascular repair (EVAR) of acute symptomatic and ruptured abdominal aortic aneurysm (rAAA) can be difficult without a large stock of suitable graft sizes. We report a prospective European multicentre study of a modular aortouniiliac stent-graft.

PATIENTS AND METHODS

Seven centres, with elective EVAR experience, participated in the study. Sixty-five patients were enrolled from September 2002 - April 2005. Some 45 patients had rAAA and 20 were acutely symptomatic. Their median age was 74 (69-80.3) years, 49 (75%) were men. From a choice of 4 body and 4 limb sizes, stent-grafts were deployed under local or general anaesthesia.

RESULTS

The endovascular delivery system was introduced and the aneurysm excluded from the circulation in a median of 40 (30-60) minutes from the first incision. The median operative duration was 150 (120-190) mins, blood loss 300 ml (200-800). 33 (51%) operations were performed by a vascular surgeon alone. There were a total of 4 (6%) peri-operative re-interventions, endovascular (n=1), open (n=2) and thrombectomy (n=1). The peri-operative mortality in the rupture group was 40% and 10% in the symptomatic group.

CONCLUSIONS

Aortouniiliac stent-grafts provide rapid exclusion of rAAA. Suitably trained surgeons can do the operation without a radiologist's support. The mortality rate from rAAA treated with EVAR remains high.

摘要

引言

如果没有大量合适尺寸的移植物库存,急性症状性和破裂性腹主动脉瘤(rAAA)的血管内修复(EVAR)可能会很困难。我们报告了一项关于模块化主动脉单髂支血管内支架移植物的前瞻性欧洲多中心研究。

患者与方法

七个有择期EVAR经验的中心参与了该研究。2002年9月至2005年4月共纳入65例患者。约45例为rAAA患者,20例为急性症状性患者。他们的中位年龄为74(69 - 80.3)岁,49例(75%)为男性。从4种主体尺寸和4种肢体尺寸中选择,在局部或全身麻醉下植入支架移植物。

结果

从第一个切口起,中位40(30 - 60)分钟内引入血管内输送系统并将动脉瘤排除在循环之外。中位手术时间为150(120 - 190)分钟,失血量300毫升(200 - 800)。33例(51%)手术仅由血管外科医生完成。围手术期共有4例(6%)再次干预,血管内(n = 1)、开放手术(n = 2)和血栓切除术(n = 1)。破裂组围手术期死亡率为40%,症状性组为10%。

结论

主动脉单髂支血管内支架移植物能快速排除rAAA。经过适当培训的外科医生无需放射科医生支持即可进行手术。EVAR治疗rAAA的死亡率仍然很高。

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