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儿童膀胱过度活动症。第2部分:管理

Overactive bladder in children. Part 2: Management.

作者信息

Franco Israel

机构信息

Section of Pediatric Urology, Department of Urology, New York Medical College, Valhalla, New York, USA.

出版信息

J Urol. 2007 Sep;178(3 Pt 1):769-74; discussion 774. doi: 10.1016/j.juro.2007.05.076. Epub 2007 Jul 13.

Abstract

PURPOSE

The management of pediatric overactive bladder syndrome has relied primarily on anticholinergics and a bowel regimen. In many cases the results have been ineffective and they have frustrated many parents, patients and practitioners. We explored other treatment modalities that may be more effective than the regimens that we currently use. A thorough understanding of the causes of overactive bladder syndrome are essential to help us find the appropriate treatment for individuals.

MATERIALS AND METHODS

We looked at numerous treatment modalities that are being used for overactive bladder syndrome and matched them to a specific cause of overactive bladder syndrome that would be best suited to treat the problem. The treatment of constipation as a mainstay for pediatric overactive bladder syndrome was explored as well as its different options. New treatment modalities involving electrical stimulation were explored as well as botulinum A toxin injections.

RESULTS

The effectiveness of each treatment was assessed, thereby providing the reader with a foundation for choosing the appropriate treatment.

CONCLUSIONS

The treatment of pediatric overactive bladder syndrome is not as simple as placing children on anticholinergics and, if there is no response, simply saying that they will outgrow it. The causes of overactive bladder syndrome are multifactorial and a better understanding of the pathophysiology will allow us to target treatments appropriately for individuals.

摘要

目的

小儿膀胱过度活动症的治疗主要依赖于抗胆碱能药物和肠道调理方案。在许多情况下,这些方法效果不佳,令许多家长、患者和从业者感到沮丧。我们探索了其他可能比目前使用的方案更有效的治疗方式。深入了解膀胱过度活动症的病因对于帮助我们为个体找到合适的治疗方法至关重要。

材料与方法

我们研究了用于膀胱过度活动症的多种治疗方式,并将它们与最适合治疗该问题的膀胱过度活动症的特定病因相匹配。探讨了将治疗便秘作为小儿膀胱过度活动症主要治疗方法及其不同选择。还研究了涉及电刺激以及肉毒杆菌A毒素注射的新治疗方式。

结果

评估了每种治疗方法的有效性,从而为读者提供选择合适治疗方法的依据。

结论

小儿膀胱过度活动症的治疗并非简单地让孩子服用抗胆碱能药物,若没有反应就简单地说他们长大后症状会自行消失。膀胱过度活动症的病因是多因素的,更好地理解其病理生理学将使我们能够为个体针对性地选择合适的治疗方法。

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