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应用弹道输尿管碎石术和闭塞性经皮气囊导管对近端输尿管大的嵌顿结石进行快速、经济的治疗:高压冲洗技术

Rapid, economical treatment of large impacted calculi in the proximal ureter with ballistic ureteral lithotripsy and occlusive, percutaneous balloon catheter: the high pressure irrigation technique.

作者信息

Dellabella M, Milanese G, d'Anzeo G, Muzzonigro G

机构信息

Department of Urology, Polytechnic University of the Marche Region, Ancona, Italy.

出版信息

J Urol. 2007 Sep;178(3 Pt 1):929-33; discussion 933-4. doi: 10.1016/j.juro.2007.05.037. Epub 2007 Jul 16.

Abstract

PURPOSE

We describe our innovative technique for the treatment of large calculi (greater than 1.5 cm) of the proximal ureter.

MATERIALS AND METHODS

Between 2003 and 2005 we positioned an 8Ch pyelostomy in 25 patients diagnosed with impacted calculi of the proximal ureter greater than 1.5 cm on ultrasound, direct x-ray of the abdomen, and/or computerized tomography and subsequent retrograde pyelography. After 30 days all patients underwent combined treatment in the Valdivia supine position, including positioning a 0.035-inch guidewire through the pyelostomy into the ureter up to above the calculus, pyelostomy removal and insertion onto the guide of a 7Ch balloon occlusion catheter, which was inflated in the ureter immediately above the calculus. Ureteral lithotripsy was done with an 8.5 to 11.5Ch ureteroscope (Wolf, Dudley, Massachusetts) with a 6Ch operating channel and a Calcusplit ballistic probe, alternating high antegrade pressure by the balloon catheter and retrograde pressure using the ureteroscope, as required. After lithotripsy and fragment dislocation the ureteroscope was retracted with rapid flow antegrade irrigation. At the end of the procedure after antegrade contrast medium followup the balloon catheter was retracted as far as the pelvis as a nephrostomy. We analyzed operative time, the number of postoperative recovery days, the incidence of complications during and after surgery, and the stone-free rate immediately, after 5 days and after 1 month.

RESULTS

Average calculus size was 1.7 cm. Ten patients presented with multiple ureteral bending upon diagnosis, which was no longer found at surgery with a consequent lack of difficult ureteroscope feeding. Significant edema downstream of the calculus was present in all cases. High pressure irrigation, a rigid ballistic probe and retrieving forceps enabled the dislocation of even larger fragments from the original calculous site in all cases. Antegrade high pressure irrigation after lithotripsy enabled the complete clearance of calcareous fragments as far as the bladder without the need for ancillary maneuvers. We observed no cases of calcareous fragment push-back. No retroperitoneal extravasation, or pyelolymphatic or pyelovenous backflow was observed. Average procedure time was 33 minutes. The renal-ureteral stone-free rate was 100% at the end of the procedure and all calcareous fragments were in the bladder. We did not observe any ureteral lesions. In no case was there onset of fever. Average postoperative hospitalization was 2 days. Followup with contrast material after 5 days showed a renal-ureteral stone-free rate of 100% and a bladder stone-free rate of 84%. The nephrostomy was removed at an average of 5.5 days.

CONCLUSIONS

Compared to the techniques described in the medical literature our method appears to have certain advantages, including a mini-invasive approach to the renal pelvis compared to that of percutaneous nephrolithotomy with protection of the renal parenchyma from high pressure, rigid ureteroscope use, which provides a high level of maneuverability and low operating costs, ballistic probe use, which provides lower costs and higher speeds than the laser, and balloon catheter use, which removes the risk of push-back and enables push-down of the fragments without any further ancillary maneuvers. The balloon catheter also enables contrast medium followup and immediate postoperative drainage. The speed of the procedure and the ability to adjust antegrade or retrograde flow with variable pressure and direction make this technique highly suitable for the complete resolution of large, impacted calculi of the proximal ureter.

摘要

目的

我们描述了一种用于治疗近端输尿管大结石(直径大于1.5厘米)的创新技术。

材料与方法

2003年至2005年间,我们对25例经超声、腹部直接X线检查和/或计算机断层扫描及随后的逆行肾盂造影诊断为近端输尿管结石嵌顿且直径大于1.5厘米的患者置入了8Ch肾盂造瘘管。30天后,所有患者在瓦尔迪维亚仰卧位接受联合治疗,包括通过肾盂造瘘管将一根0.035英寸的导丝置入输尿管至结石上方,拔除肾盂造瘘管并将一根7Ch球囊阻塞导管沿导丝置入,在结石上方的输尿管中充盈球囊。使用带有6Ch操作通道的8.5至11.5Ch输尿管镜(Wolf,达德利,马萨诸塞州)和Calcusplit弹道探头进行输尿管碎石术,根据需要通过球囊导管交替施加高顺行压力并使用输尿管镜施加逆行压力。碎石和碎片移位后,通过快速顺行冲洗将输尿管镜撤回。在手术结束时,经顺行造影剂随访后,将球囊导管撤回至肾盂作为肾造瘘管。我们分析了手术时间、术后恢复天数、手术期间及术后并发症的发生率以及即刻、术后5天和术后1个月的结石清除率。

结果

结石平均大小为1.7厘米。10例患者在诊断时存在多处输尿管弯曲,手术时未再发现,因此输尿管镜插入未遇到困难。所有病例结石下游均有明显水肿。高压冲洗、刚性弹道探头和取石钳在所有病例中均能使甚至更大的碎片从原结石部位移位。碎石术后的顺行高压冲洗能够将钙质碎片完全清除至膀胱,无需辅助操作。我们未观察到钙质碎片回推的病例。未观察到腹膜后外渗、肾盂淋巴或肾盂静脉逆流。平均手术时间为33分钟。手术结束时肾输尿管结石清除率为100%,所有钙质碎片均在膀胱内。我们未观察到任何输尿管损伤。无一例出现发热。平均术后住院时间为2天。术后5天的造影剂随访显示肾输尿管结石清除率为100%,膀胱结石清除率为84%。肾造瘘管平均在5.5天拔除。

结论

与医学文献中描述的技术相比,我们的方法似乎具有某些优势,包括与经皮肾镜取石术相比对肾盂的微创入路,可保护肾实质免受高压,使用刚性输尿管镜具有较高的可操作性且手术成本低,使用弹道探头成本低于激光且速度更快,使用球囊导管可消除碎片回推风险且无需任何进一步辅助操作即可使碎片下移。球囊导管还可进行造影剂随访并在术后立即引流。该手术的速度以及通过可变压力和方向调节顺行或逆行流量的能力使其非常适合于完全解决近端输尿管大的嵌顿结石。

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