Kosugi Shigeki, Mizumachi Syoko, Kitajima Akiko, Igarashi Takumi, Hamada Takamasa, Kaya Hitoshi, Kurihara Kazunao, Ogasawara Koji, Sakata Hitomi, Yamamoto Masahiro, Nagamine Mamoru, Yamazaki Hiroyuki
Division of Hematology, Kawaguchi Municipal Medical Center.
Intern Med. 2007;46(14):1135-8. doi: 10.2169/internalmedicine.46.0014. Epub 2007 Jul 17.
A 73-year-old man with suspected lymphoproliferative disorder was introduced to our hospital. The patient demonstrated palpable hard masses in the abdomen. Enhanced computed tomography of the abdomen and pelvis revealed a bulky mass of para-aortic lymph nodes. Biopsy of left-sided supraclavicular lymph nodes revealed metastatic adenocarcinoma. Serum tumor markers were examined, revealing prostate-specific antigen (PSA) levels of 3,354.0 ng/ml. Rectal examinations revealed a stony-hard prostatic mass. Biopsy of the prostate disclosed poorly to moderately differentiated adenocarcinoma. Although metastases to the supraclavicular lymph nodes are rare in prostate cancer, it should be distinguished from malignant lymphoma and other malignancies.
一名73岁疑似淋巴增殖性疾病的男性被转诊至我院。患者腹部可触及硬块。腹部和盆腔增强计算机断层扫描显示腹主动脉旁淋巴结有一个巨大肿块。左侧锁骨上淋巴结活检显示为转移性腺癌。检测血清肿瘤标志物,结果显示前列腺特异性抗原(PSA)水平为3354.0 ng/ml。直肠检查发现前列腺有一个如石般坚硬的肿块。前列腺活检显示为低分化至中分化腺癌。尽管前列腺癌转移至锁骨上淋巴结较为罕见,但仍应与恶性淋巴瘤及其他恶性肿瘤相鉴别。