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弥漫性单侧亚急性神经视网膜炎

Diffuse unilateral subacute neuroretinitis.

作者信息

Anshu Arundhati, Chee Soon Phaik

机构信息

Singapore National Eye Centre, 11, Third Hospital Avenue, Singapore 168751, Singapore.

出版信息

Int Ophthalmol. 2008 Apr;28(2):127-9. doi: 10.1007/s10792-007-9117-y. Epub 2007 Jul 19.

Abstract

BACKGROUND

In patients with diffuse unilateral subacute neuroretinitis (DUSN), the presence and, therefore, clinical visualization of subretinal nematode makes the diagnosis obvious. However when located under the retinal pigment epithelium (RPE), diagnosis is presumptive and challenging. We report a case of presumed DUSN to illustrate this diagnostic dilemma and to highlight the clinical signs which suggest the diagnosis.

METHODS

Case report of a patient with DUSN.

RESULTS

In our patient the nematode was not located subretinally and this made the diagnosis difficult. However, the appearance of sub-RPE serpiginous tract in the infero-temporal retina, peripheral RPE hypopigmentation and good clinical response to anti-helminthics supported the diagnosis.

CONCLUSIONS

It is important to have a high index of suspicion when patients present with a combination of above findings. This will help in early control of ocular inflammation and salvaging vision.

摘要

背景

在弥漫性单侧亚急性神经视网膜炎(DUSN)患者中,视网膜下线虫的存在及其临床可见性使得诊断较为明确。然而,当线虫位于视网膜色素上皮(RPE)下方时,诊断具有推测性且颇具挑战性。我们报告一例疑似DUSN病例,以说明这一诊断困境并强调提示该诊断的临床体征。

方法

对一名DUSN患者的病例报告。

结果

在我们的患者中,线虫并非位于视网膜下,这使得诊断困难。然而,颞下视网膜RPE下匐行性病灶的外观、周边RPE色素减退以及对抗蠕虫药的良好临床反应支持了该诊断。

结论

当患者出现上述多种表现时,保持高度怀疑指数很重要。这将有助于早期控制眼部炎症并挽救视力。

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