LigaSure与传统电凝痔切除术的随机临床试验。

Randomized clinical trial of LigaSure and conventional diathermy haemorrhoidectomy.

作者信息

Muzi M G, Milito G, Nigro C, Cadeddu F, Andreoli F, Amabile D, Farinon A M

机构信息

Department of Surgery, Tor Vergata University Hospital, Rome, Italy.

出版信息

Br J Surg. 2007 Aug;94(8):937-42. doi: 10.1002/bjs.5904.

DOI:10.1002/bjs.5904

PMID:17636512

Abstract

BACKGROUND

The aim of this randomized prospective trial was to compare LigaSure and conventional diathermy haemorrhoidectomy.

METHODS

Two hundred and eighty-four patients with grade III or IV haemorrhoids were randomized to LigaSure or diathermy (Milligan-Morgan) haemorrhoidectomy as a day-case procedure. Operating time, postoperative pain score, hospital stay, postoperative complications, wound healing time and time to return to normal activities were assessed. Thirty-four patients were lost to follow-up.

RESULTS

The mean operating time for LigaSure haemorrhoidectomy was significantly shorter than that for diathermy (P = 0.011). Patients treated with LigaSure had significantly less postoperative pain (measured on a visual analogue scale; P = 0.010), a shorter wound healing time (defined as time to absence of swelling; P = 0.012) and less time off work (P = 0.010) than patients who had diathermy. Neither postoperative complications nor mean hospital stay (day-case surgery) were significantly different.

CONCLUSION

LigaSure haemorrhoidectomy demonstrates simplicity, reproducibility, a low complication rate, fast wound healing, a quick return to work and reduced postoperative pain.

摘要

背景

这项随机前瞻性试验的目的是比较LigaSure痔切除术和传统透热疗法痔切除术。

方法

284例III级或IV级痔疮患者被随机分为接受LigaSure痔切除术或透热疗法（Milligan-Morgan）痔切除术，作为日间手术。评估手术时间、术后疼痛评分、住院时间、术后并发症、伤口愈合时间以及恢复正常活动的时间。34例患者失访。

结果

LigaSure痔切除术的平均手术时间显著短于透热疗法（P = 0.011）。与接受透热疗法的患者相比，接受LigaSure治疗的患者术后疼痛明显减轻（采用视觉模拟评分法测量；P = 0.010），伤口愈合时间更短（定义为肿胀消失的时间；P = 0.012），误工时间更少（P = 0.010）。术后并发症和平均住院时间（日间手术）均无显著差异。