Davenport M, Ure B M, Petersen C, Kobayashi H
King's College Hospital, London, United Kingdom.
Eur J Pediatr Surg. 2007 Jun;17(3):180-3. doi: 10.1055/s-2007-965147.
Initial surgical therapy of biliary atresia (BA) consists of the radical excision of extrahepatic remnants and portoenterostomy. However, despite this procedure, which was introduced by Kasai, BA remains the commonest indication for paediatric liver transplantation. The goal of the work group on the technical aspects of Kasai portoenterostomy procedures during the European Biliary Atresia Registry Conference 2007 was to achieve consensus on various operative and perioperative aspects relevant for paediatric surgeons. Although there is still disagreement regarding some of the technical details of the Kasai operation, a remarkable consensus has emerged in most areas of the actual surgery. No consensus was achieved on the role of postoperative drainage, the routine application of steroids, the use of oral prophylactic antibiotics, and the treatment of postoperative cholangitis. Nevertheless, the wide variation in reported results, which was a feature of this conference, suggests that there are still areas where improvement in outcomes can be anticipated by changes in technique or practice.
胆道闭锁(BA)的初始手术治疗包括肝外残余组织的根治性切除和肝门空肠吻合术。然而,尽管有由Kasai引入的这种手术,但BA仍然是小儿肝移植最常见的适应证。在2007年欧洲胆道闭锁登记会议期间,Kasai肝门空肠吻合术技术方面工作组的目标是就小儿外科医生相关的各种手术和围手术期方面达成共识。尽管对于Kasai手术的一些技术细节仍存在分歧,但在实际手术的大多数领域已出现显著的共识。关于术后引流的作用、类固醇的常规应用、口服预防性抗生素的使用以及术后胆管炎的治疗尚未达成共识。然而,本次会议的一个特点是报告结果差异很大,这表明仍有一些领域可通过技术或实践的改变来预期改善结果。