齿状回之谜

Enigmas of the dentate gyrus.

作者信息

Leutgeb Jill K, Moser Edvard I

机构信息

Centre for the Biology of Memory, Norwegian University of Science and Technology, N-7489, Trondheim, Norway.

出版信息

Neuron. 2007 Jul 19;55(2):176-8. doi: 10.1016/j.neuron.2007.07.002.

DOI:10.1016/j.neuron.2007.07.002

PMID:17640520

Abstract

We are rapidly approaching a better understanding of the mechanisms that allow our brains to form distinct representations for similar events or episodes. McHugh et al. have brought that goal one step closer by showing that NMDA receptor-dependent synaptic plasticity in the dentate gyrus is necessary for immediate differentiation between environments with similar features.

摘要

我们正在迅速接近对大脑为相似事件或情节形成不同表征的机制的更好理解。麦克休等人通过表明齿状回中依赖N-甲基-D-天冬氨酸（NMDA）受体的突触可塑性对于具有相似特征的环境之间的即时区分是必要的，从而使这一目标又迈进了一步。