Lai Sue-Min, Duncan Pamela W, Keighley John, Johnson Dallas
Department of Preventive Medicine, University of Kansas Medical Center, Kansas City, KS 66160-7313, USA.
J Rehabil Res Dev. 2002 Sep-Oct;39(5):589-96.
This study examined the relationship between depressive symptoms and time courses in achieving independence in basic activities of daily living (BADL) and instrumental activities of daily living (IADL).
At baseline, 1, 3, and 6 months after stroke, 459 stroke patients were prospectively assessed. We used the Geriatric Depression Scale to determine depressive status. Outcomes were times to achieve independence in BADL (Barthel >95) and independ-ence in at least three IADL. We used the Kaplan-Meier method and time-dependent Cox proportional hazards regression to examine the relationship between depression and stroke recovery.
Depressed patients were 0.3 times less likely than nondepressed patients to achieve BADL of >95 and 0.4 times less likely to be independent in three or more IADL. The cumulative percentages for the nondepressed patients to achieve a BADL of >95 at 1, 3, and 6 months after stroke were 47%, 63%, and 72%, and for the depressed patients, they were 19%, 34%, and 52%, respectively. Similarly, the cumulative percentages for nondepressed patients to achieve complete independence in three or more IADL at 1, 3, and 6 months after stroke were 56%, 72%, and 85%, and for the depressed patients, they were 32%, 47%, and 72%, respectively. Depressed patients had poorer recovery patterns and took longer to achieve the outcomes.
Stroke patients with depressive symptoms progressed slower in achieving independence of BADL and IADL compared to patients without depressive symptoms.
本研究探讨了抑郁症状与在基本日常生活活动(BADL)和工具性日常生活活动(IADL)中实现独立的时间进程之间的关系。
在中风后的基线、1个月、3个月和6个月,对459名中风患者进行前瞻性评估。我们使用老年抑郁量表来确定抑郁状态。结果指标为达到BADL独立(Barthel指数>95)的时间以及至少三项IADL达到独立的时间。我们使用Kaplan-Meier方法和时间依赖性Cox比例风险回归来研究抑郁与中风恢复之间的关系。
与非抑郁患者相比,抑郁患者达到BADL>95的可能性降低0.3倍,在三项或更多IADL中实现独立的可能性降低0.4倍。中风后1个月、3个月和6个月,非抑郁患者达到BADL>95的累积百分比分别为47%、63%和72%,而抑郁患者分别为19%、34%和52%。同样,中风后1个月、3个月和6个月,非抑郁患者在三项或更多IADL中实现完全独立的累积百分比分别为56%、72%和85%,而抑郁患者分别为32%、47%和72%。抑郁患者的恢复模式较差,实现结果所需时间更长。
与无抑郁症状的患者相比,有抑郁症状的中风患者在实现BADL和IADL独立方面进展较慢。