来自加尔各答的伤寒沙门氏菌血清型伤寒杆菌的噬菌体分型、生物分型及抗菌药物耐药谱
Phage typing, biotyping & antimicrobial resistance profile of Salmonella enterica serotype Typhi from Kolkata.
作者信息
Sen Bhaswati, Dutta Shanta, Sur Dipika, Manna Byomkesh, Deb A K, Bhattacharya S K, Niyogi S K
机构信息
National Institute of Cholera & Enteric Diseases (ICMR), Kolkata, India.
出版信息
Indian J Med Res. 2007 May;125(5):685-8.
BACKGROUND & OBJECTIVE: Kolkata and its suburbs in eastern India are known to be endemic for typhoid fever. The objective of this study was to determine phage types, biotypes and antimicrobial resistance patterns of Salmonella enterica serotype Typhi isolated during the period 2003-2005 from a prospective surveillance for typhoid fever in two urban slums in Kolkata.
METHODS
A total of 195 Salmonella enterica serotype Typhi isolated from blood cultures were phage typed, biotyped and tested for their antimicrobial susceptibility profile.
RESULTS
Phage type E1 was the most common (60.3%) followed by phage type A among five phage types identified. Biotype I (95%) was predominant, 28 isolates were multidrug resistant (MDR) and most of the MDR strains belonged to phage type E1 and biotype I.
INTERPRETATION & CONCLUSION: A single phage type and biotype were prevalent among the Salmonella enterica serotype Typhi isolates studied from Kolkata, India.
背景与目的
印度东部的加尔各答及其郊区是伤寒热的地方性流行区。本研究的目的是确定2003年至2005年期间从加尔各答两个城市贫民窟的伤寒热前瞻性监测中分离出的肠炎沙门氏菌伤寒血清型的噬菌体类型、生物型和抗菌药物耐药模式。
方法
对从血培养中分离出的195株肠炎沙门氏菌伤寒血清型进行噬菌体分型、生物分型，并检测其抗菌药物敏感性。
结果
在鉴定出的五种噬菌体类型中，E1型噬菌体最为常见（60.3%），其次是A型噬菌体。生物型I（95%）占主导地位，28株分离株对多种药物耐药（MDR），且大多数MDR菌株属于E1型噬菌体和生物型I。
解读与结论
在印度加尔各答研究的肠炎沙门氏菌伤寒血清型分离株中，单一的噬菌体类型和生物型普遍存在。
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