一名急性淋巴细胞白血病患儿的BK病毒所致肾小管间质性肾炎
BK virus-induced tubulointerstitial nephritis in a child with acute lymphoblastic leukemia.
作者信息
Inaba Hiroto, Jones Deborah P, Gaber Lillian W, Shenep Jerry L, Call Sandra K, Pui Ching-Hon, Razzouk Bassem I
机构信息
Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-2794, USA.
出版信息
J Pediatr. 2007 Aug;151(2):215-7. doi: 10.1016/j.jpeds.2007.05.005.
Abstract
We report a case of BK virus-induced tubulointerstitial nephritis in a child with acute lymphoblastic leukemia. Primary BK virus infection was exacerbated by chemotherapy-induced immunodeficiency. Careful administration of chemotherapy and anti-viral therapy prevented further damage. This diagnosis should be considered in children who experience renal dysfunction during cancer treatment.
摘要
我们报告了一例急性淋巴细胞白血病患儿发生BK病毒诱导的肾小管间质性肾炎的病例。化疗引起的免疫缺陷加剧了原发性BK病毒感染。谨慎给予化疗和抗病毒治疗可防止进一步损伤。对于癌症治疗期间出现肾功能障碍的儿童应考虑这一诊断。
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