Harling R, Pearce M, Chandrakumar M, Mueller K, Hayward A
Centre for Infectious Disease Epidemiology, Department of Primary Care and Population Science, University College London, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK.
Public Health. 2007 Nov;121(11):822-7. doi: 10.1016/j.puhe.2007.02.019. Epub 2007 Jul 23.
To describe the uptake and outcomes of a service for tuberculosis screening of asylum seekers.
Descriptive study.
A tuberculosis screening service was established at the Dover Induction Centres for all asylum seekers entering the UK through ports in Kent. This study describes the uptake and completion of tuberculosis screening, the results of tuberculin skin testing and follow-up, and the cost of the service during its first year.
In 1 year, 8258 asylum seekers were screened: 94% of 8799 who were eligible. A total of 2.2% of those with completed screens were positive (on the basis of symptoms requiring further investigation or positive Heaf reaction). Eleven cases of active respiratory disease were diagnosed on the basis of symptoms, Heaf reaction plus chest X-ray, or both; three were confirmed microbiologically. One-quarter of Heaf tests were not read because of the rapid dispersal of asylum seekers. The follow-up of those requiring further investigations at their destinations was largely unknown. The service cost was 350,000 pounds.
Induction centre tuberculosis screening services for asylum seekers can achieve a high uptake, but their cost-effectiveness is questionable, particularly where the yield of active disease is low. Tuberculin skin testing is not an ideal screening procedure in this setting because it may be uncompleted and the benefit of detecting latent infections is uncertain.
描述一项针对寻求庇护者的结核病筛查服务的接受情况及结果。
描述性研究。
在多佛尔入境中心为所有经肯特郡各港口进入英国的寻求庇护者设立了一项结核病筛查服务。本研究描述了结核病筛查的接受情况与完成情况、结核菌素皮肤试验结果及后续跟进情况,以及该服务第一年的成本。
在1年时间里,对8258名寻求庇护者进行了筛查,占符合条件的8799人的94%。在完成筛查的人员中,共有2.2%呈阳性(基于需要进一步调查的症状或希夫反应呈阳性)。根据症状、希夫反应加胸部X光检查或两者综合,诊断出11例活动性呼吸道疾病病例;其中3例经微生物学确诊。由于寻求庇护者迅速分散,四分之一的希夫试验未得到解读。对于那些在目的地需要进一步调查的人员,后续情况大多不明。该服务成本为35万英镑。
为寻求庇护者设立的入境中心结核病筛查服务可以实现高接受率,但其成本效益值得怀疑,尤其是在活动性疾病检出率较低的情况下。在这种情况下,结核菌素皮肤试验并非理想的筛查程序,因为它可能无法完成,而且检测潜伏感染的益处也不确定。