Godart F
Service des maladies cardiovasculaires infantiles et congenitales, Hopital cardiologique, CHRU de Lille, 59037 Lille cedex.
Arch Mal Coeur Vaiss. 2007 May;100(5):478-83.
Classical treatment of coarctation of the aorta consists of resection and suture through a left thoracotomy. However, over the last 20 years, balloon angioplasty, recently associated with stenting, has progressively supplanted surgery in the adult both in native forms and in recoarctions. Usually, the diameters of the balloon and stent are chosen to be the same as that of the aortic isthmus or proximal aortic arch without exceeding that of the aorta at the diaphragm. Moreover, the tendency now is to recommend stenting in cases of severe, tubular and long stenosis associated with proximal hypoplasia and in cases of residual gradients after dilatation. The complications of percutaneous techniques are the risk of restenosis (11-15%), aneurysm formation (5%), and a very small risk of dissection. However, it is recognised that stenting is associated with fewer complications than dilatation alone or surgery. After correction, the main problem is that of hypertension, often associated with persistence of a pressure gradient at the isthmus. Coarctation is often associated with a congenital bicuspid aortic valve in nearly 50% of cases and the valvular condition may progress to stenosis or incompetence requiring corrective surgery. In these cases, a dilatation of the aorta must also be suspected which may progress to an aneurysm. In addition, pregnancy is often complicated by maternal hypertension. The consequences are a high risk of abortion and, for the child, a prematurity, poor growth, and a small risk of recurrence of the cardiac disease. Pregnant women should be followed up in a multidisciplinary fashion and, when possible, problems of residual stenosis, aneurysm and hypertension should be controlled and corrected before the woman wishes to be pregnant. In practice, medium and long term follow up should be undertaken by specialist teams and comprise clinical examination, blood pressure investigations on effort and by ambulatory recording, Doppler ultrasonography of the aortic arch and aortic valve and MRI which has become the reference examination for the aortic arch. After the initial investigations, these tests should be repeated every 2 or 5 years in adults or sooner depending on the results of the initial work-up.
主动脉缩窄的传统治疗方法是通过左胸切口进行切除和缝合。然而,在过去20年中,球囊血管成形术(最近与支架置入术联合应用)在成人原发性和再缩窄性主动脉缩窄的治疗中已逐渐取代了手术治疗。通常,球囊和支架的直径选择与主动脉峡部或主动脉弓近端相同,但不超过膈肌水平的主动脉直径。此外,目前的趋势是,对于伴有近端发育不全的严重、管状且长段狭窄以及扩张后仍有残余压差的病例,建议进行支架置入术。经皮技术的并发症包括再狭窄风险(11 - 15%)、动脉瘤形成(5%)以及极轻微的夹层风险。然而,人们认识到,与单纯扩张或手术相比,支架置入术的并发症更少。矫正后,主要问题是高血压,通常与峡部持续存在压力差有关。主动脉缩窄在近50%的病例中常伴有先天性二叶主动脉瓣,瓣膜病变可能进展为狭窄或关闭不全,需要进行矫正手术。在这些情况下,还必须怀疑主动脉扩张,其可能进展为动脉瘤。此外,妊娠常并发母体高血压。后果是流产风险高,对胎儿而言,则有早产、生长发育不良以及心脏病复发的小风险。孕妇应以多学科方式进行随访,并且在可能的情况下,在妇女希望怀孕之前,应控制和纠正残余狭窄、动脉瘤和高血压问题。实际上,应由专业团队进行中长期随访,包括临床检查、运动时和动态血压记录、主动脉弓和主动脉瓣的多普勒超声检查以及MRI,MRI已成为主动脉弓的参考检查方法。在进行初步检查后,这些检查在成人中应每2年或5年重复一次,或根据初始检查结果更早进行重复检查。