Li Ming, Zhang Guo-An, Liu Ying
Department of Burns, Jishuitan Hosptial, Beijing 100035, P. R. China.
Zhonghua Shao Shang Za Zhi. 2007 Apr;23(2):91-3.
To analyze the strains of bacteria in burn infection and their resistance to antibiotics in our burn unit in the recent years.
Bacteria were isolated from specimens from the wounds, venous lines, blood, urine and feces of the hospitalized burn patients from January 2003 to December 2005 to analyze the vicissitude of bacteria and their drug resistance.
The number of Gram-negative bacteria (372 strains) was larger than Gram-positive ones (292 strains). Staphylococcus aureus (accounting for 16.7%) was predominant among Gram-positive bacteria, among which methicillin resistant staphylococcus aureus (MRSA) accounted for 82.5%. Among the Gram-negative bacteria, Pseudomonas aeruginosa accounted for 12.5%, and Escherichia coli accounted for 11.1%. The drug resistant ESPL-producing strains of Escherichia coli and Klebsiella pneumoniae accounted for 60.8% and 42.9%, respectively.
Drug resistance to antibiotics is a serious problem in a burn unit, calling for monitoring the vicissitude of bacteria strains and antibiotics sensitivity in order to control bacterial infection and dissemination.
分析近年来我院烧伤科烧伤感染的细菌菌株及其对抗生素的耐药性。
对2003年1月至2005年12月住院烧伤患者的创面、静脉导管、血液、尿液和粪便标本进行细菌分离，分析细菌的变迁及其耐药情况。
革兰阴性菌（372株）多于革兰阳性菌（292株）。革兰阳性菌中金黄色葡萄球菌占主导（占16.7%），其中耐甲氧西林金黄色葡萄球菌（MRSA）占82.5%。革兰阴性菌中铜绿假单胞菌占12.5%，大肠埃希菌占11.1%。产超广谱β-内酰胺酶（ESBL）的大肠埃希菌和肺炎克雷伯菌耐药菌株分别占60.8%和42.9%。
烧伤科抗生素耐药是一个严重问题，需要监测菌株变迁及抗生素敏感性，以控制细菌感染和传播。
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